Faculty Members

Dr.SAFAR MORAYA SAFAR ALQAHTANI

Associate Professor Department of Pharmaceutical Chemistry College of Pharmacy AL-Kharj

Kharj
011-588-8888
safar.alqahtani@psau.edu.sa

Curriculum Vitae
Publications

Publications

1. Alamri, M.A., Ahmad, S., Alqahtani, S.M., Irfan, M., Alabbas, A.B. and Tahir ul Qamar, M., 2022. Screening of marine natural products for potential inhibitors targeting biotin biosynthesis pathway in Mycobacterium tuberculosis. Journal of Biomolecular Structure and Dynamics, pp.1-9.
2. Alqahtani, S.M., Altharawi, A., Altamimi, M.A., Alossaimi, M.A. Mahdi, W.A., Mohhammad Ramzan, M., Hussain, A., 2022. Method Development, Stability, and Pharmacokinetic Studies of Acyclovir-Loaded Topical Formulation in Spiked Rat Plasma. Processes, 10, 2079.
3. Alamri, M.A., Tahir ul Qamar, M., Alabbas, A.B., Alqahtani, S.M., Alossaimi, M.A., Azam, S., Hashmi, M.H. and Rajoka, M.S.R., 2022. Molecular and Structural Analysis of Specific Mutations from Saudi Isolates of SARS-CoV-2 RNA-Dependent RNA Polymerase and their Implications on Protein Structure and Drug–Protein Binding. Molecules, 27(19), p.6475.
4. Abbas, A., Anwar, F., Alqahtani, S.M., Ahmad, N., Al-Mijalli, S.H., Shahid, M. and Iqbal, M., 2022. Hydro-Distilled and Supercritical Fluid Extraction of Eucalyptus camaldulensis Essential Oil: Characterization of Bioactives Along With Antioxidant, Antimicrobial and Antibiofilm Activities. Dose-Response, 20(3), p.15593258221125477.
5. Riadi, Y., Alamri, M.A., Geesi, M.H., Anouar, E.H., Ouerghi, O., Alabbas, A.B., Alossaimi, M.A., Altharawi, A., Dehbi, O. and Alqahtani, S.M., 2022. Synthesis, characterization, biological evaluation and molecular docking of a new quinazolinone-based derivative as a potent dual inhibitor for VEGFR-2 and EGFR tyrosine kinases. Journal of Biomolecular Structure and Dynamics, 40(15), pp.6810-6816.
6. Alabbas, A.B., Alqahtani, S.M., Panda, S.S., Alrobaian, M., Altharawi, A., Almalki, W.H., Barkat, M.A., Rub, R.A., Rahman, M., Mir Najib Ullah, S.N. and Beg, S., 2022. Development of a Validated UPLC–MS/MS Method for Simultaneous Estimation of Neratinib and Curcumin in Human Plasma: Application to Greenness Assessment and Routine Quantification. Journal of Chromatographic Science.
7. Alqahtani, S.M., Altharawi, A., Alabbas, A.B., Alossaimi, M.A., Kamal, M., Alasmary, F.A. and Alamri, M.A., 2022. Evaluation of Haloxylon Persicum Leaves Ethanolic Extract for Phytochemical, Antioxidant, Anticancer, and Antimicrobial Properties. Current Topics in Nutraceutical Research, 20(2).
8. Shahroz, M.M., Sharma, H.K., Altamimi, A.S., Alamri, M.A., Ali, A., Ali, A., Alqahtani, S., Altharawi, A., Alabbas, A.B., Alossaimi, M.A. and Riadi, Y., 2022. Novel and Potential Small Molecule Scaffolds as DYRK1A Inhibitors by Integrated Molecular Docking-Based Virtual Screening and Dynamics Simulation Study. Molecules, 27(4), p.1159.
9. A ALOSSAIMI, M., Altamimi, A.S.A., ALQAHTANI S.M., Hassan, Mohd.Z., Rashid, M., Kamal, M., Afzal, O., 2022. HPLC Method Development and Validation for the Estimation of Thymoquinone in Nigella sativa Seed Extract by Quality by Design (QbD) Approach. Latin American Journal of Pharmacy, 41, 1110-8.
10. Chadar, R., Afzal, O., Alqahtani, S.M. and Kesharwani, P., 2021. Carbon nanotubes as an emerging nanocarrier for the delivery of doxorubicin for improved chemotherapy. Colloids and Surfaces B: Biointerfaces, 208, p.112044.
11. Alamri, M.A., Tahir Ul Qamar, M., Mirza, M.U., Bhadane, R., Alqahtani, S.M., Muneer, I., Froeyen, M. and Salo-Ahen, O.M., 2021. Pharmacoinformatics and molecular dynamics simulation studies reveal potential covalent and FDA-approved inhibitors of SARS-CoV-2 main protease 3CLpro. Journal of Biomolecular Structure and Dynamics, 39(13), pp.4936-4948.
12. Alamri, M.A., Alafnan, A.D., Afzal, O., Alabbas, A.B. and Alqahtani, S.M., 2021. Structure Prediction of SPAK C-terminal Domain and Analysis of its Binding to RFXV/I Motifs by Homology Modelling, Docking and Molecular Dynamics Simulation Studies. Current Computer-Aided Drug Design, 17(5), pp.666-675.
13. Altamimi, A.S., El-Azab, A.S., Abdelhamid, S.G., Alamri, M.A., Bayoumi, A.H., Alqahtani, S.M., Alabbas, A.B., Altharawi, A.I., Alossaimi, M.A. and Mohamed, M.A., 2021. Synthesis, Anticancer Screening of Some Novel Trimethoxy Quinazolines and VEGFR2, EGFR Tyrosine Kinase Inhibitors Assay; Molecular Docking Studies. Molecules, 26(10), p.2992.
14. Alamri, M.A., ul Qamar, M.T., Afzal, O., Alabbas, A.B., Riadi, Y. and Alqahtani, S.M., 2021. Discovery of anti-MERS-CoV small covalent inhibitors through pharmacophore modeling, covalent docking and molecular dynamics simulation. Journal of Molecular Liquids, 330, p.115699.
15. Alamri, M.A., ul Qamar, M.T., Mirza, M.U., Alqahtani, S.M., Froeyen, M. and Chen, L.L., 2020. Discovery of human coronaviruses pan-papain-like protease inhibitors using computational approaches. Journal of pharmaceutical analysis, 10(6), pp.546-559.
16. Alasmary, F.A., Awaad, A.S., Alqahtani, S.M., El-Meligy, R.M., Abdullah, D.A. and Alqasoumi, S.I., 2020. Evaluation of the chemical constituents and potential biological activities of Cunninghamella blakesleeana. Saudi Pharmaceutical Journal, 28(10), pp.1197-1202.
17. Alamri, M.A., Altharawi, A., Alabbas, A.B., Alossaimi, M.A. and Alqahtani, S.M., 2020. Structure-based virtual screening and molecular dynamics of phytochemicals derived from Saudi medicinal plants to identify potential COVID-19 therapeutics. Arabian Journal of Chemistry, 13(9), pp.7224-7234.
18. ul Qamar, M.T., Alqahtani, S.M., Alamri, M.A. and Chen, L.L., 2020. Structural basis of SARS-CoV-2 3CLpro and anti-COVID-19 drug discovery from medicinal plants. Journal of pharmaceutical analysis, 10(4), pp.313-319.
19. Abdel-Gawad, S.A. and Alqahtani, S.M., 2020. Ultra-performance liquid chromatography–tandem mass spectrometric determination of ramipril in human plasma. Tropical Journal of Pharmaceutical Research, 19(4), pp.851-857.
20. Alamri, M.A., ul Qamar, M.T. and Alqahtani, S.M., 2020. Pharmacoinformatics and molecular dynamic simulation studies reveal potential inhibitors of SARS-CoV-2 main protease 3CLpro.
21. Alqahtani, S., Roberts, C.J., Stolnik, S. and Bosquillon, C., 2020. Development of an in vitro system to study the interactions of aerosolized drugs with pulmonary mucus. Pharmaceutics, 12(2), p.145.
22. Alqahtani, S.M., Alamri, M.A., Alabbas, A., Alam, P., Abdel-Gawad, S.A., Shakeel, F. and Alasmary, F.A., 2020. Spectrophotometric and spectrodensitometric quantification of a new antiviral combination. JPC–Journal of Planar Chromatography–Modern TLC, 33(1), pp.79-87.
23. Kamal, M., Jawaid, T., Alqahtani, S.M., Hassan, M.Z., Yusuf, M., 2020. Synthesis and Anticonvulsant Activity of Some New Proline-Benzofuran-Acetamide/Propanamide/Butanamide Hybrids, INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 30, 93-98.
24. Tahir ul Qamar, M., Saleem, S., Ashfaq, U.A., Bari, A., Anwar, F. and Alqahtani, S., 2019. Epitope‐based peptide vaccine design and target site depiction against Middle East Respiratory Syndrome Coronavirus: an immune-informatics study. Journal of translational medicine, 17(1), pp.1-14.
25. Cingolani, E., Alqahtani, S., Sadler, R.C., Prime, D., Stolnik, S. and Bosquillon, C., 2019. In vitro investigation on the impact of airway mucus on drug dissolution and absorption at the air-epithelium interface in the lungs. European Journal of Pharmaceutics and Biopharmaceutics, 141, pp.210-220.
26. Wood, M.J., Kim, D.D.H., Alqahtani, M.S., Smith, D.S., Barrett, P.D., Grundy, P.R. and Rahman, D.R., 2017. PP38. LIMITATION OF EXTERNAL LIPID SOURCES INDUCES DIFFERENTIAL PROLIFERATIVE AND MORPHOLOGICAL RESPONSES IN ADULT AND PAEDIATRIC GBM CELLS. Neuro-oncology, 19(suppl_1), pp.i11-i11.
27. Wood, J., Kim, D., Alqahtani, S., Smith, S., Barrett, D., Grundy, R. and Rahman, R., 2016. P01. 04 Adult and paediatric GBM cells show differential phenotypic responses to external lipoprotein deprivation.
28. Mohsin, K., Al-Qahtani, S. and Alanazi, F.K., 2014. Rapid and sensitive bioanalytical stability-indicating method for quantification of talinolol, a selective β1 adrenoceptor antagonist in lipid based formulations using ultrafast UHPLC systems. Acta poloniae pharmaceutica, 71(5), p.737.
29. Alabbas, A.B., Alqahtani, S.M. and Akiel, M.A., Integrative Subtractive Proteomics, Immunoinformatics, Docking and Simulation Approaches, Reveals Candidate Vaccine against Sin Nombre Orthohantavirus. Frontiers in Immunology, p.6640.
30. MUBARAK ALAMRI, A.A., Alabbas, M.A.A. and Safar, M.A., Structure-Based Virtual Screening and Molecular Dynamics of Phytochemicals Derived from Saudi Medicinal Plants to Identify Potential COVID-19 Therapeutics.

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Dr.SAFAR MORAYA SAFAR ALQAHTANI

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Faculty Members

Dr.SAFAR MORAYA SAFAR ALQAHTANI

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