Faculty Members

دكتوراة في علوم السرطان Assistant Professor Department of Medical Laboratory Sciences College of Applied Medical Sciences in Alkharj

2017: PhD candidate in cancer studies at University of Manchester, Manchester, UK, (in progress) 2015: MSc, Cancer Studies, Collage of Sciences, North Carolina University, Greensboro, USA 2000: BSc, Biochemistry, Collage of Sciences, King Abdulaziz University, Jeddah, KSA

Breast cancer is the most common cancer in women worldwide, with 2.26 million yearly new cases. Moreover, 1 in every 8 women in the UK will develop BC at some point in their lifetime. BC survival rate is improving but it remains the fourth highest cause of female death in the UK. Statistics showed that more than 11,500 people died per year of the disease in the period between 2016-1018, demonstrating the need for more efficient treatments. One key approach to reduce mortality figures is cancer prevention. Multiple breast cancer risk factors have been identified including female sex, age, gene postmenopausal obesity, presence of benign breast disease and high mammographic density. Risk factors include certain mutations as BRCA1 and BRCA2 mutations. However, among these factors only mammographic density and obesity are modifiable. However, it is not known how high dense tissue results in breast cancer initiation or progression, or the mechanisms by which the anti-estrogen tamoxifen reduces mammographic density. Tamoxifen reduces the incidence of breast cancer, but only in those women who experience a reduction in mammographic density during the first year of treatment. I am interested in identifying gene expression and proteomic signatures of mammographic density resistance in women receiving preventive tamoxifen.

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