Faculty Members

Prof.Abdulmalik Saleh Alfawaz Altamimi

Professor Department of Pharmaceutical Chemistry College of Pharmacy AL-Kharj

Kharj
011-588-6072
as.altamimi@psau.edu.sa

Curriculum Vitae
Publications

Education

- 1433: Ph.D. Pharmaceutical Sciences [Pharmaceutical Chemistry], King Saud University, Riyadh, Saudi Arabia. - 1422: M.Sc. Pharmaceutical Sciences [Pharmacology], King Saud University, Riyadh, Saudi Arabia. - 1415: B.Sc. Pharmaceutical Sciences, King Saud University, Riyadh, Saudi Arabia.

Research Interests

medicinal chemistry and synthesis of novel pharmaceutical compounds

Experience

01-2-1443 - until now - Professor of Pharmaceutical Chemistry - Prince Sattam bin Abdulaziz University
16-6-1438 - 01-2-1443 - Associate Professor of Pharmaceutical Chemistry - Prince Sattam bin Abdulaziz University
1-4-1434 - 16-6-1438 - Assistant Professor of Pharmaceutical Chemistry - Prince Sattam bin Abdulaziz University

Responsibilities

Chairman of Pharmaceutical Chemistry Department, College of Pharmacy, Prince Sattam bin Abdulaziz University since 16-11-1437-till now. Vice Dean of Scientific Research 1-6-1435 – 30-5-1437 Chairman of Pharmaceutical Chemistry Department, College of Pharmacy, Prince Sattam bin Abdulaziz University 18-10-1434 -30-5-1435. Assistant Professor of Pharmaceutical Chemistry [Medicinal Chemistry], Prince Sattam bin Abdulaziz University, Al-Kharj since 1-4-1434. 1415-1432: A lot of administrative positions at the Ministry of Health.

Publications

1 Al-Tamimi AM, Bari A, Al-Omar MA, Alrashood KA, El-Emam AA. 3-(1-Adamant-yl)-1-{[4-(2-meth-oxy-phen-yl)piperazin-1-yl]meth-yl}-4-methyl-1H-1,2,4-triazole-5(4H)-thione. Acta Crystallogr Sect E Struct Rep Online 66 Pt 7 o1756 2010
2 Al-Tamimi AM, Bari A, Al-Omar MA, El-Emam AA, Ng SW. N'-[(2-n-Butyl-4-chloro-1H-imidazol-5-yl)-methyl-idene]adamantane-1-carbo-hydrazide sesquihydrate ethanol hemi-solvate. Acta Crystallogr Sect E Struct Rep Online. 66 Pt 8 o2131 2010
3 Ali A. El-Emam, Abdul-Malek S. Al-Tamimi, Khalid A. Al-Rashood, Hriday N. Misra, Vijay Narayan, Onkar Prasad, Leena Sinha. Structural and spectroscopic characterization of a novel potential chemotherapeutic agent 3-(1-adamantyl)-1-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-4-methyl-1H-1,2,4-triazole-5(4H)-thione by first principle calculations. Journal of Molecular Structure 1022 49-60 2012
4 El-Emam AA, Al-Omar MA, Al-Tamimi AM, Ng SW, Tiekink ER. 3-(Adamantan-1-yl)-1-[(4-benzyl-piperazin-1-yl)meth-yl]-4-[(E)-(2-hy-droxy-benzyl-idene)amino]-1H-1,2,4-triazole-5(4H)-thione. Acta Crystallogr Sect E Struct Rep Online 68 Pt 6 o1766-7 2012
5 El-Emam AA, Alrashood KA, Al-Omar MA, Al-Tamimi AM. Synthesis and antimicrobial activity of N'-heteroarylidene-1-adamantylcarbohydrazides and (±)-2-(1-adamantyl)-4-acetyl-5-[5-(4-substitutedphenyl-3-isoxazolyl)]-1,3,4-oxadiazolines. Molecules 17 3 3475-83 2012
6 El-Emam AA, Alrashood KA, Al-Tamimi AM, Ng SW, Tiekink ER. 3-(Adamantan-1-yl)-1-[(4-ethyl-piperazin-1-yl)meth-yl]-4-[(E)-(4-hy-droxy-benzyl-idene)amino]-1H-1,2,4-triazole-5(4H)-thione. Acta Crystallogr Sect E Struct Rep Online 68 Pt 3 o657-8 2012
7 El-Emam AA, Al-Omar MA, Al-Tamimi AM, Ng SW, Tiekink ER. 3-(Adamantan-1-yl)-4-methyl-1-[(4-phenyl-piperazin-1-yl)meth-yl]-1H-1,2,4-triazole-5(4H)-thione dichloro-methane hemisolvate. Acta Crystallogr Sect E Struct Rep Online 68 Pt 6 o1772-3 2012
8 Abdul-Malek S. Al-Tamimi, Ahmed M. Alafeefy, Ali A. El-Emam, Seik Weng Ng and Edward R. T. Tiekink. 5-(Adamantan-1-yl)-N-methyl-1,3,4-thiadiazol-2-amine. Acta Crystallogr Sect E Struct Rep Online 69 Pt 5 o683 2013
9 El-Emam AA, Al-Tamimi AM, Al-Omar MA, Alrashood KA, Habib EE. Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. Eur J Med Chem. 68 96-102 2013
10 Abdul-Malek S. Al-Tamimi, Ebtehal S. Al-Abdullah, Ali A. El-Emam, Seik Weng Ng and Edward R. T. Tiekink. 3-(Adamantan-1-yl)-4-[(E)-(2,6-difluorobenzylidene) amino]-1-[(4-ethylpiperazin-1-yl)methyl]-4,5—dihydro-1H-1,2,4-triazole-5-thione. Acta Crystallogr Sect E Struct Rep Online 69 Pt 5 o685–o686 2013
11 Abdul-Malek S. Al-Tamimi, Omar A. Al-Deeb, Ali A. El-Emam, Seik Weng Ng and Edward R. T. Tiekink. 5-(Adamantan-1-yl)-3-anilinomethyl]-2,3—dihydro-1,3,4-oxadiazole-2-thione. Acta Crystallogr Sect E Struct Rep Online 69 Pt 5 o729 2013
12 Abdul-Malek S. Al-Tamimi, Ahmed M. Alafeefy, Ali A. El-Emam, Seik Weng Ng and Edward R. T. Tiekink. 5-(Adamantan-1-yl)-3-[(4-fluoroanilino)methyl]-2,3—dihydro-1,3,4-oxadiazole-2-thione. Acta Crystallogr Sect E Struct Rep Online 69 Pt 5 o730 2013
13 Ali A. El-Emam, Abdul-Malek S. Al-Tamimi, Khalid A.Alrashood, Seik Weng Ng . and Edward R. T. Tiekink. 3-(Adamantan-1-yl)-4-methyl-1-({4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-methyl)-4,5-dihydro-1H-1,2,4-triazole-5-thione. Acta Crystallogr Sect E Struct Rep Online 69 Pt 5 o695–o696 2013
14 Abdul-Malek S. Al-Tamimi, Ebtehal S. Al-Abdullah,Ali A. El-Emam, Seik Weng Ng and Edward R. T.Tiekink, 3-(Adamantan-1-yl)-4-[(E)-(2,6-difluorobenzylidene)amino]-1-[(4-ethylpiperazin-1-yl)methyl]-4,5-dihydro-1H-1,2,4-triazole-5-thione, Acta Crystallogr Sect E Struct Rep Online. 69 Pt 5 o685–o686 2013
15 Mary YS, Al-Tamimi AM, El-Brollosy NR, El-Emam AA, Jojo PJ, Panicker CY, Van Alsenoy C. Molecular structure and vibrational spectra of 2-Ethoxymethyl-6-ethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione, a potential chemotherapeutic agent, by density functional methods. SPECTROCHIMICA ACTA PART A. 133 439-448 2014
16 Alafeefy AM, Ceruso M, Al-Tamimi AM, Del Prete S, Capasso C, Supuran CT. Quinazoline-sulfonamides with potent inhibitory activity against the alpha-carbonic anhydrase from Vibrio cholera. BIOORGANIC & MEDICINAL CHEMISTRY. 22 5133-5140 2014
17 Sert Y, El-Emam AA, Al-Abdullah ES, Al-Tamimi AM, Cirak C, Ucun F. Use of vibrational spectroscopy to study 4-benzyl-3-(thiophen-2-yl)-4,5-dihydro-1H-1,2,4-triazole-5-thione: A combined theoretical and experimental approach. SPECTROCHIMICA ACTA PART A. 126 280-290 2014
18 Al-Tamimi AM, El-Emam AA, Al-Deeb OA, Prasad O, Pathak SK, Srivastava R, Sinha L. Structural and spectroscopic characterization of a novel potential anti-inflammatory agent 3-(adamantan-1-yl)-4-ethyl-1H-1,2,4- triazole-5(4H)thione by first principle calculations. SPECTROCHIMICA ACTA PART A. 124 108-123 2014
19 Alafeefy AM, Abdel-Aziz HA, Vullo D, Al-Tamimi AM, Al-Jaber NA, Capasso C, Supuran CT. Inhibition of carbonic anhydrases from the extremophilic bacteria Sulfuri hydrogenibium yellostonense (SspCA) and S. azorense (SazCA) with a new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b][1,3,4]thiadiazinyl-or2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl moieties. Bioorganic Med Chem. 22(1):141-7. 1 2014
20 Murat Bozdag , Ahmed M. Alafeefy , Daniela Vullo , Fabrizio Carta , Nurcan Dedeoglu ,Abdul-Malek S. Al-Tamimi , Nabila A. Al-Jaber , Andrea Scozzafava , Claudiu T. Supuran , Benzenesulfonamides incorporating bulky aromatic/heterocyclic tails with potent carbonic anhydrase inhibitory activity, Bioorganic & Medicinal Chemistry 23 7751–7764 2015
21 Alafeefy AM, Ceruso, M, Al-Tamimi AM, Del Prete S, Supuran CT, Capasso C. Inhibition studies of quinazoline-sulfonamide derivatives against the gamma-CA (PgiCA) from the pathogenic bacterium, Porphyromonas gingivalis. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY. 30 4 592-596 2015
22 Alafeefy AM, Abdel-Aziz HA, Vullo D, Al-Tamimi AM, Awaad AS, Mohamed MA, Capasso C, Supuran CT. Inhibition of human carbonic anhydrase isozymes I, II, IX and XII with a new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b][1,3,4]thiadiazinyl- or 2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl moieties. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY. 30 1 52-56 2015
23 Sebastian SSHR, Al-Tamimi AM, El-Brollosy NR, El-Emam AA, Panicker, CY, Van Alsenoy C. Vibrational spectroscopic (FT-IR and FT-Raman) studies, HOMO-LUMO, NBO analysis and MEP of 6-methyl-1-({[(2E)-2-methyl-3-phenyl-prop-2-en-l-yl]oxy}methyl)-1,2,3,4-tetra-hydroquinazoline-2,4-dione, a potential chemotherapeutic agent, using density functional methods. SPECTROCHIMICA ACTA PART A. 134 316-325 2015
24 Abdul-Malek S. Al-Tamimi, Electronic structure, hydrogen bonding and spectroscopic profile of a new 1,2,4-triazole-5(4H)-thione derivative: A combined experimental and theoretical (DFT) analysis, Journal of Molecular Structure 1120 215-227 2016
25 Murat Bozdag , Ahmed M. Alafeefy , Fabrizio Carta , Mariangela Ceruso , Abdul-Malek S. Al-Tamimi, Abdulla A. Al-Kahtani , Fatmah A. S. Alasmary , Claudiu T. Supuran Synthesis 4-[2-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-ethyl]-benzenesulfonamides with subnanomolar carbonic anhydrase II and XII inhibitory properties, Bioorganic & Medicinal Chemistry 24 4100–4107 2016
26 Ahmed M. Alafeefy , Fabrizio Carta , Mariangela Ceruso , Abdul-Malek S. Al-Tamimi ,Abdulla A. Al-Kahtani , Claudiu T. Supuran, Development of 3-(4-aminosulphonyl)-phenyl-2-mercapto-3H-quinazolin-4-ones as inhibitors of carbonic anhydrase isoforms involved in tumorigenesis and glaucoma, Bioorganic & Medicinal Chemistry 24 1402–1407 2016
27 Monirah A. Al-Alshaikh, Hazem A. Ghabbour, Abdul-Malek S. Al-Tamimi, Mohammed S.M. Abdelbaky, Santiago Garcia-Granda and Ali A. El-Emam, Crystal structure of 5-(adamantan-1-yl)-3-[(4-chloroanilino)methyl]-2,3-dihydro-1,3,4-oxadiazole-2-thione, C19H22ClN3OS, Z. Kristallogr. NCS 231 301-303 2016
28 Ahmed M. Alafeefy , Rehan Ahmad , Maha Abdulla , Wagdy M. Eldehna ,Abdul-Malek S. Al-Tamimi , Hatem A. Abdel-Aziz , Omar Al-Obaid , Fabrizio Carta ,Abdulla A. Al-Kahtani , Claudiu T. Supuran Development of certain new 2-substituted-quinazolin-4-ylaminobenzenesulfonamide as potential antitumor agents, European Journal of Medicinal Chemistry 109 247-253 2016
29 Ebtehal S. Al-Abdullah, Hazem A. Ghabbour, Hamad M. Alkahtani, Abdul-Malek S. Al-Tamimi and Ali A. El-Emam, Crystal structure of N-(adamantan-1-yl)-4-phenylpiperazine-1-carbothioamide, C21H29N3S, Z. Kristallogr. NCS 231 3 991–993 2016
30 Haya I. Aljohar, Hazem A. Ghabbour, Abdul-Malek S. Al-Tamimi, Haitham AlRabiah and Ali A. El-Emam, Crystal structure of 4-[(E)-(2-chloro-6-fluorobenzylidene)amino] -1,2-dihydro-2,3-dimethyl-1-phenylpyrazol-5-one, C18H15ClFN3O, Z. Kristallogr. NCS 231 3 777–780 2016
31 Abdul-Malek S. Al-Tamimi, Hazem A. Ghabbour and Ali A. El-Emam, Crystal structure of N'-(adamantan-2-ylidene)pyridine-3-carbohydrazide, C16H19N3O, Z. Kristallogr. NCS 231 2 573–575 2016
32 Abdul-Malek S. Al-Tamimi, Hazem A. Ghabbour and Ali A. El-Emam, Crystal structure of 6-oxo-4-propyl-2-(propylthio)-1,6-dihydropyrimidine-5-carbonitrile, C11H15N3OS, Z. Kristallogr. NCS 231 2 583–585 2016
33 Murat Bozdag, Ahmed Mahmoud Alafeefy, Abdul Malik Altamimi, Fabrizio Carta, Claudiu T. Supuran, Daniela Vullo., Synthesis of new 3-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-benzenesulfonamides with strong inhibition properties against the tumor associated carbonic anhydrases IX and XII. Bioorganic & Medicinal Chemistry 25 2782–2788 2017
34 Murat Bozdag, Ahmed Mahmoud Alafeefy, Abdul Malik Altamimi, Daniela Vullo, Fabrizio Carta,Claudiu T. Supuran., Coumarins and other fused bicyclic heterocycles with selective tumorassociated carbonic anhydrase isoforms inhibitory activity, Bioorganic and Medicinal Chemistry, 25 2 677-683 2017
35 Lamya H. Al-Wahaibi, NuriÖztürk, Hanan M. Hassan, Yusuf Sertd, Ali A. El- Emam, Abdul-Malek S. Al-Tamimi, Halil Gökce, Experimental (FT-IR, Laser-Raman and NMR) and theoretical comparative study on 2-benzylsulfanyl-4-pentyl-6-(phenylsulfanyl)pyrimidine-5-carbonitrile, a potential bioactive agent, Journal of Theoretical and Computational Chemistry, 17
1850035 2018
36 Dehbi, O.; Ishak, E. A.; Bakht, M. A.; Geesi, M. H.; Alshammari, M. B.; Chagnault, V.; Kaiba, A.; Lazar, S.; Altamimi A. M. S.; Riadi, Y, Water-mediated synthesis of disubstituted 5-aminopyrimidines from vinyl azides under microwave irradiation. Green Chem. Lett. Rev. 2018, 11, 62 (Corrigendum) GREEN CHEMISTRY LETTERS AND REVIEWS, 11 2 165 2018
37 Abdul-Malek S. Al-Tamimi , Y. Sheena Mary, Pankaj B. Miniyar, Lamya H. Al-Wahaibi, Ali A. El-Emam, Stevan Armakovi, Sanja J. Armakovi. Synthesis, spectroscopic analyses, chemical reactivity and molecular docking study and anti-tubercular activity of pyrazine and condensed oxadiazole derivatives, Journal of Molecular Structure, 1164 459-469 2018
38 Ozlem Akgul, Lorenzo Di Cesare Mannelli, Daniela Vullo, Andrea Angeli, Carla Ghelardini, Gianluca Bartolucci, Abdulmalik Saleh Alfawaz Altamimi, Andrea Scozzafava, Claudiu T. Supuran, and Fabrizio Carta, Discovery of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs−CAIs) for the Management of Rheumatoid Arthritis J. Med. Chem. 61 4961−4977 2018
39 Ahsan, M. J.; Choupra, A.; Sharma, R. K.; Jadav, S. S.; Padmaja, P.; Hassan, M.; Al-Tamimi, A.; Geesi, M. H.; Bakht, M. A. Rationale Design, Synthesis, Cytotoxicity Evaluation, and Molecular Docking Studies of 1, 3, 4-oxadiazole Analogues. Anti-Cancer Agents Med. Chem. (Formerly Curr. Med. Chem. Agents) 18 121–138 2018
40 M. J. Ahsan, R. P. Yadav, S. Saini, Mohd. Z. Hassan, M. A. Bakht, S. S. Jadav, A. B. S. Al-Tamimi, M. H. Geesi, Md Y.Ansari, H. Khalilullah, Y. Riadi, Synthesis, Cytotoxic Evaluation, and Molecular Docking Studies of New Oxadiazole Analogues, Lett. Org. Chem. 15 49–56 2018
41 Abdul-Malek S. Al-Tamimi, Y. Sheena Mary, Hanan M. Hassan c, K.S. Resmi , Ali A. El-Emam d, B. Narayana, B.K. Sarojini, Study on the structure, vibrational analysis and molecular docking of fluorophenyl derivatives using FT-IR and density functional theory computations, Journal of Molecular Structure, 1164 172-179 2018
42 Abdul-Malek S. Altamimi, Ahmed M. Alafeefy, Agnese Balode, Igor Vozny, Aleksandrs Pustenko, Mohey Eldin El Shikh, Fatmah A. S. Alasmary, Sherif A. Abdel-Gawad & Raivis Žalubovskis, Symmetric molecules with 1,4-triazole moieties as potent inhibitors of tumour-associated lactate dehydrogenase-A., Journal of Enzyme Inhibition and Medicinal Chemistry 33
1 147-150 2018
43 Abdul-Malek S. Al-Tamimi, Mikel Etxebeste-Mitxeltoren, Carmen Sanmartin, Antonio Jimenez-Ruiz, Leo Syrjanen, Seppo Parkkila, Silvia Selleri, Fabrizio Carta, Discovery of new organoselenium compounds as antileishmanial agents, Bioorganic Chemistry, 86
339–345 2019
44 Claudiu T. Supuran, Abdulmalik Saleh Alfawaz Altamimi & Fabrizio Carta, Carbonic anhydrase inhibition and the management of glaucoma: a literature and patent review 2013-2019. Expert Opinion on Therapeutic Patents, 29
781-792 2019
45 Murat Bozdag, Abdulmalik Saleh Alfawaz Altamimi, Daniela Vullo, Claudiu T. Supuran, Fabrizio Carta,
State of the Art on Carbonic Anhydrase Modulators for Biomedical Purposes, Current Medicinal Chemistry, 26
2558 – 2573 2019
46 Murat Bozdag, Marta Ferraroni, Carol Ward, Fabrizio Carta, Silvia Bua, Andrea Angeli, Simon P. Langdon, Ian H. Kunkler, Abdul-Malek S. Al-Tamimi, Claudiu T. Supuran. Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast, European Journal of Medicinal Chemistry 182 111600 2019
47 Y. Kalisha Vali, Rambabu Gundla, Om V. Singh, Yasinalli Tamboli, Lorenzo Di Cesare Manelli, Carla Ghelardini, Abdul-Malek S. Al-Tamimi, Fabrizio Carta, Andrea Angelie, Claudiu T. Supurane,
Spirocyclic sulfonamides with carbonic anhydrase inhibitory and antineuropathic pain activity, Bioorganic Chemistry, 92 103210 2019
48 Lamya H. Al-Wahaibi, Nandakumar Santhosh Kumar, Ali A. El-Emam, Natarajan S. Venkataramanan, Hazem A. Ghabbour, Abdul-Malek S. Al-Tamimi, Investigation of potential anti-malarial lead candidate 2-(4- fluorobenzylthio)-5-(5-bromothiophen-2-yl)-1,3,4-oxadiazole: Insights from crystal structure, DFT, QTAIM and hybrid QM/MMbinding energy analysis, Journal of Molecular Structure 1175 230-240 2019
49 Mohamed Jawed Ahsan, Rupesh Kumar Kumawat, Surender Singh Jadav, Mohammed H. Geesi, Mohammed Afroz Bakht, Mohd. Zaheen Hassan, Abdulmalik Bin Saleh Al-Tamimi, Yassine Riadi , Salahuddin, Afzal Hussain, Narayan Murthy Ganta, Habibullah Khalilullah Mohamed, H. K. Synthesis, Cytotoxic Evaluation, and Molecular Docking Studies of N-(7- Hydroxy-4-methyl-2-oxoquinolin-1(2H)-yl)acetamide/benzamide Analogues. Lett. Drug Des. Discov. 16 2 182-193 2019
50 GAMAL A. SOLIMAN, SHERIF A. ABDEL-GAWAD, MOHD N. ANSARI, ABDUL-MALEK S. ALTAMIMI, HOSSNY A. EL-BANNA, HISHAM Y. ELZORBA, NOHA F. HASSAN, The Potential Cardioprotective Effect of Matricaria Chamomilla Extract Against Diabetes-Induced Oxidative Stress in Rats. FARMACIA, 68 269-279 2020
51 Andrea Angelia, Thomas S. Peat, Silvia Selleri, Abdulmalik Saleh Alfawaz Altamimi, Claudiu T. Supurana, Fabrizio Cartaa. X-ray crystallography of Epacadostat in adduct with Carbonic Anhydrase IX, Bioorganic Chemistry, 97 103669 2020
52 Alfawaz, Abdulmalik Saleh; Bawa, Sandhya; Athar, Fareeda; Hassan, Md Quamrul; Riadi, Yassine; Afzal, Obaid. Pyrrolidin‐2‐one linked benzofused heterocycles as novel small molecule monoacylglycerol lipase inhibitors and antinociceptive agents Chemical Biology & Drug Design 96 6 1418-1432. 2020
53 Zhang, Ying; Zhao, Jing; Afzal, Obaid; Kazmi, Imran; Abbasi, Fahad A. Al‐; Altamimi, Abdulmalik S. A.; Yang, Zhen; Neuroprotective role of chrysin‐loaded poly(lactic‐co‐glycolic acid) nanoparticle against kindling‐induced epilepsy through Nrf2/ARE/HO‐1 pathway Journal of Biochemical and Molecular Toxicology 35 2 e22634 2020
54 Rahman M, Almalki WH, Afzal O, Alfawaz Altamimi AS, Kazmi I, Al-Abbasi FA, Choudhry H, Alenezi SK, Barkat MA, Beg S, Kumar V, Alhalmi A; Cationic Solid Lipid Nanoparticles of Resveratrol for Hepatocellular Carcinoma Treatment: Systematic Optimization, in vitro Characterization and Preclinical Investigation International Journal of Nanomedicine 15 9283-9299 2020
55 Shiroorkar, Predeepkumar Narayanappa; Afzal, Obaid; Kazmi, Imran; Al-Abbasi, Fahad A.; Altamimi, Abdulmalik Saleh Alfawaz; Gubbiyappa, Kumar Shiva; Sreeharsha, Nagaraja; Cardioprotective Effect of Tangeretin by Inhibiting PTEN/AKT/mTOR Axis in Experimental Sepsis-Induced Myocardial Dysfunction Molecules 25 23 5622 2020
56 Shi, Zonghua; Alrobaian, Majed; Kazmi, Imran; Afzal, Obaid; Altamimi, Abdulmalik Saleh Alfawaz; Al-Abbasi, Fahad A; Almalki, Waleed H; Baothman, Abdullah A; Choudhry, Hani; Rahman, Mahfoozur; Cationic self-nanoemulsifying formulations of tamoxifen with improved biopharmaceutical attributes and anticancer activity: Systematic development and evaluation Journal of Molecular Liquids 320 114534 2020
57 Beg, Sarwar; Malik, Ankit K; Afzal, Obaid; Altamimi, Abdulmalik Saleh Alfawaz; Kazmi, Imran; Al-Abbasi, Fahad A; Almalki, Waleed H; Barkat, Md Abul; Kawish, SM; Pradhan, Debi Prasad; Systematic Development and Validation of a RP-HPLC Method for Estimation of Abiraterone Acetate and its Degradation Products Journal of Chromatographic Science 59 1 79-87 2021
58 Rahman, Mahfoozur; Almalki, Waleed H; Kazmi, Imran; Afzal, Obaid; Katouah, Hanadi A; Alrobaian, Majed; Altamimi, Abdulmalik Saleh Alfawaz; Al-Abbasi, Fahad A; Alshammari, Mohammed S; Rub, Rehan Abdur; Development and validation of a new UPLC-MS/MS method for quantification of ganoderic acid-A loaded nanolipidic carrier in rat plasma and application to pharmacokinetic studies Journal of Chromatography B 1163 122501 2021
59 Rahman, Mahfoozur; Almalki, Waleed H; Afzal, Obaid; Kazmi, Imran; Altamimi, Abdulmalik Saleh Alfawaz; Alghamdi, Saad; Al-Abbasi, Fahad A; Altowayan, Waleed M; Alrobaian, Majed; Alharbi, Khalid S; Diosmin-loaded solid nanoparticles as nano-antioxidant therapy for management of hepatocellular carcinoma: QbD-based optimization, in vitro and in vivo evaluation Journal of Drug Delivery Science and Technology 61 102213 2021
60 Mohammad Islamuddin, Obaid Afzal, Wajihul Hasan Khan, Malik Hisamuddin, Abdulmalik Saleh Alfawaz Altamimi, Ibraheem Husain, Kentaro Kato, Mubarak A Alamri, Shama Parveen Inhibition of Chikungunya Virus Infection by 4-Hydroxy-1-Methyl-3-(3-morpholinopropanoyl)quinoline-2(1H)-one (QVIR) Targeting nsP2 and E2 Proteins ACS omega 6 14 9791–9803 2021
61 Beg, Sarwar; Kazmi, Imran; Afzal, Obaid; Altamimi, Abdulmalik Saleh Alfawaz; Al-Abbasi, Fahad A; Almalki, Waleed H; Alghamdi, Saad; Alrobaian, Majed; Alharbi, Khalid S; Alshammari, Mohammed S; Implications of phospholipid-based nanomixed micelles of olmesartan medoxomil with enhanced lymphatic drug targeting ability and systemic bioavailability Journal of Drug Delivery Science and Technology 62 102273 2021
62 Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Mir Mohammad Shahroz, Hemant Kumar Sharma, Yassine Riadi, Md Quamrul Hassan Analgesic and Anticancer Activity of Benzoxazole Clubbed 2-Pyrrolidinones as Novel Inhibitors of Monoacylglycerol Lipase Molecules 26 8 2389 2021
63 Mohammad Khalid, Mohammed H. Alqarni, Ambreen Shoaib, Muhammad Arif, Ahmed I. Foudah, Obaid Afzal, Abuzer Ali, Amena Ali, Saad S. Alqahtani, Abdulmalik S. A. Altamimi Anti-Arthritic and Anti-Inflammatory Potential of Spondias mangifera Extract Fractions: An In Silico, In Vitro and In Vivo Approach Plants 10 5 825 2021
64 Mohammad Rashid, Obaid Afzal, Altamimi, Abdulmalik Saleh Alfawaz BENZIMIDAZOLE MOLECULE HYBRID WITH OXADIAZOLE RING AS ANTIPROLIFERATIVE AGENTS: IN-SILICO ANALYSIS, SYNTHESIS AND BIOLOGICAL EVALUATION Journal of the Chilean Chemical Society 66 2 5164-5182 2021
65 Yang Gao, Waleed H. Almalki, Obaid Afzal, Sunil K. Panda, Imran Kazmi, Majed Alrobaian, Hanadi A. Katouah, Abdulmalik Saleh Alfawaz Altamimi, Fahad A. Al-Abbasi, Sultan Alshehri, Kriti Soni, Ibrahim Abdel Aziz Ibrahim, Mahfoozur Rahman, Beg Sarwar Systematic development of lectin conjugated microspheres for nose-to-brain delivery of rivastigmine for the treatment of Alzheimer’s disease Biomedicine & Pharmacotherapy 141 111829 2021
66 Afzal Hussain, Obaid Afzal, Abdulmalik S.A. Altamimi, Raisuddin Ali Application of green nanoemulsion to treat contaminated water (bulk aqueous solution) with azithromycin Environmental Science and Pollution Research 28 61696–61706 2021
67 Bin Wang, Lin Sun, Mingyun Wen, Youchun Tan, Waleed H Almalki, Hanadi Katouah, Imran Kazmi, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Fahad A. Al-Abbasi, Majed Alrobaian, Khalid S Alharbi, Sattam K Alenezi, Adel F. Alghaith, Sarwar Beg, Rahman Mahfoozur Nano lipidic carriers for codelivery of sorafenib and ganoderic acid for enhanced synergistic antitumor efficacy against hepatocellular carcinoma Saudi Pharmaceutical Journal 29 8 843-856 2021
68 Afzal Hussain, Sultan Alshehri, Mohd Ramzan, Obaid Afzal, Abdulmalik S. A. Altamimi, Manal A. Alossaimi Biocompatible solvent selection based on thermodynamic and computational solubility models, in-silico GastroPlus prediction, and cellular studies of ketoconazole for subcutaneous delivery Journal of Drug Delivery Science and Technology 65 102699 2021
69 Shadab Md, Nabil A Alhakamy, Mohamed A Alfaleh, Obaid Afzal, Abdulmalik SA Altamimi, Ashif Iqubal, Rasheed A Shaik Mechanisms Involved in Microglial-Interceded Alzheimer’s Disease and Nanocarrier-Based Treatment Approaches Journal of Personalized Medicine 11 11 1116 2021
70 Lihua Chen, Majed Alrobaian, Obaid Afzal, Imran Kazmi, Sunil K. Panda, Abdulmalik Saleh Alfawaz Altamimi, Fahad A. Al-Abbasi, Waleed H. Almalki, Hanadi A. Katouah, Tanuja Singh, Kriti Soni, Abdul Hafeez, Sarwar Beg, Vikas Kumar, Mahfoozur Rahman Crotamiton-loaded tea tree oil containing phospholipid-based microemulsion hydrogel for scabies treatment: in vitro, in vivo evaluation, and dermatokinetic studies Drug Delivery 28 1 1972-1981 2021
71 Oussama ouerghi, Mohammed H. Geesi, Abdellah Kaibaa, El Hassane Anouar, Abdul-Malek S. Al-Tamimi, Philippe Guionneaud, Elmutasim O Ibnouf, Rachid Azzallou, Md Afroz Bakht, Yassine Riadi. Synthesis, antibacterial evaluation, crystal structure and molecular interactions analysis of new 6-Bromo-2 chloro 3-butylquinazolin-4(3H)-one. Journal of Molecular Structure 1225 129166 2021
72 Obaid Afzal, Tuhfa, Mubarak A. Alamri, Abdulmalik S. A. Altamimi, Abdul Roouf Bhat,
Fareeda Athar Thiazolidinone Derivatives: Synthesis, Characterization, Antimicrobial
Evaluation, and Cytotoxicity Studies Indian Journal of Heterocyclic Chemistry 31 4 621-634 2021
73 Vetriselvan Subramaniyan, Shivkanya Fuloria, Gaurav Gupta, Darnal Hari Kumar, Mahendran Sekar, Kathiresan Sathasivam, Kalvatala Sudhakar, Khalid Saad Alharbi, Waleed Hassan Al-Malki, Obaid Afzal, Imran Kazmi, Fahad A. Al-Abbasi, Abdulmalik Saleh Alfawaz Altamimi, Neeraj Kumar Fuloria A review on epidermal growth factor receptor's role in breast and non-small cell lung cancer Chemico-Biological Interactions 351 109735 2022
74 Yassine Riadi, Obaid Afzal, Abdul-Malek S Al-Tamimi, Abuzer Ali, Amena Ali Ultrasonic-Mediated Green Synthesis of Novel S-Arylated-Pyridopyrimidines and Antimicrobial Evaluation against Escherichia coli and Staphylococcus aureus Polycyclic Aromatic Compounds 42 9 6546-6553 2022
75 Shumin Li, Zhongkai Xu, Majed Alrobaian, Obaid Afzal, Imran Kazmi, Waleed H. Almalki, Abdulmalik Saleh Alfawaz Altamimi, Fahad A. Al-Abbasi, Khalid S Alharbi, Waleed M Altowayan, Tanuja Singh, Md Habban Akhter, Manish Gupta, Mahfoozur Rahman, Sarwar Beg EGF-functionalized lipid-polymer hybrid nanoparticles of 5-Fluorouracil and Sulphoraphane with enhanced bioavailability and anticancer activity against colon carcinoma Biotechnology and Applied Biochemistry 69 5 2205-2221 2022
76 Afzal Hussain, Mohammad A. Altamimi, Obaid Afzal, Abdulmalik S. A. Altamimi, Abuzer Ali, Amena Ali, Fleming Martinez, Mohd Usman Mohd Siddique, William E. Acree Jr., Abolghasem Jouyban Preferential Solvation Study of the Synthesized Aldose Reductase Inhibitor (SE415) in the {PEG 400 (1) + Water (2)} Cosolvent Mixture and GastroPlus-Based Prediction ACS Omega 7
1
1197–1210 2022
77 Afzal Hussain, Obaid Afzal, Abdulmalik S.A. Altamimi, Abuzer Ali, Amena Ali, Fleming Martinez, Mohd Usman Mohd Siddique, William E. Acree Jr, Naushad Ali Preferential solvation study of (Z)-N-benzyl-2-{5-(4-hydroxybenzylidene)-2,4-dioxothiazolidin-3-yl)acetamide(3) in {NMP (1) + Water (2)} co-solvent mixture and GastroPlus software based in vitro simulation Journal of Molecular Liquids 349 118491 2022
78 Md Habban Akhter, Irfan Ahmad, Mohammad Y. Alshahrani, Alhanouf I. Al-Harbi, Habibullah Khalilullah, Obaid Afzal, Abdulmalik S.A. Altamimi, Shehla N.M. Najib Ullah, Abhijeet Ojha, Shahid Karim Drug Delivery Challenges and Current Progress in Nanocarrier-Based Ocular Therapeutic System Gels 8 2 82 2022
79 Abdul-Malek S. Al-Tamimi, Yassine Riadi. Microwave-Assisted Synthesis of Novel Antimicrobial N-Arylated-Pyridopyrimidines, Polycyclic Aromatic Compounds 42 6 3339-3347 2022
80 Mir Mohammad Shahroz, Hemant Kumar Sharma, Abdulmalik S. A. Altamimi, Mubarak A. Alamri, Abuzer Ali, Amena Ali, Safar Alqahtani, Ali Altharawi, Alhumaidi B. Alabbas, Manal A. Alossaimi, Yassine Riadi, Ahmad Firoz, Obaid Afzal* Novel and Potential Small Molecule Scaffolds as DYRK1A Inhibitors by Integrated Molecular Docking-Based Virtual Screening and Dynamics Simulation Study Molecules
27 4 1159 2022
81 Mohammad Islamuddin, Abuzer Ali, Obaid Afzal, Amena Ali, Intzar Ali, Abdulmalik Saleh Alfawaz Altamimi, Mubarak A. Alamri, Kentaro Kato, and Shama Parveen Thymoquinone Induced Leishmanicidal Effect via Programmed Cell Death in Leishmania donovani ACS Omega 7 12 10718-10728 2022
82 Khalid Saad Alharbi, Yogendra Singh, Waleed Hassan Almalki, Sushama Rawat, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Imran Kazmi, Fahad A. Al-Abbasi, Sami I. Alzarea, Sachin Kumar Singh, Shvetank Bhatt, Dinesh Kumar Chellappan, Kamal Dua, Gaurav Gupta Gut Microbiota Disruption in COVID-19 or Post-COVID Illness Association with severity biomarkers: A Possible Role of Pre / Pro-biotics in manipulating microflora Chemico-Biological Interactions 358 109898 2022
83 Shahid Karim, Md Habban Akhter, Abdulhadi S. Burzangi, Huda Alkreathy, Basma Alharthy, Sabna Kotta, Shadab Md, Md Abdur Rashid, Obaid Afzal, Abdulmalik S. A. Altamimi, Habibullah Khalilullah Phytosterol-Loaded Surface-Tailored Bioactive-Polymer Nanoparticles for Cancer Treatment: Optimization, In Vitro Cell Viability, Antioxidant Activity, and Stability Studies Gels 8 4 219 2022
84 Kumar Venkatesan, Nazima Haider, Mohammad Yusuf, Afzal Hussain, Obaid Afzal, Sabina Yasmin, Abdulmalik S.A. Altamimi Water/transcutol/lecithin/M− 812 green cationic nanoemulsion to treat oxytetracycline contaminated aqueous bulk solution Journal of Molecular Liquids 357 119154 2022
85 Mohammad Arshad Javed Shaikh, Khalid Saad Alharbi, Waleed Hassan Almalki, Syed Sarim Imam, Mohammed Albratty, Abdulkarim M. Meraya, Sami I. Alzarea, Imran Kazmi, Fahad A. Al-Abbasi, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Yogendra Singh, Sachin Kumar Singh, Kamal Dua, Gaurav Gupta Sodium alginate based drug delivery in management of breast cancer Carbohydrate Polymers 292 119689 2022
86 Mayank Handa, Waleed H. Almalki, Rahul Shukla, Obaid Afzal, AbdulMalik Saleh Alfawaz Altamimi, Sarwar Beg, Mahfoozur Rahman Active pharmaceutical ingredients (APIs) in ionic liquids: an effective approach for API physiochemical parameter optimization Drug Discovery Today 27 9 2415-2424 2022
87 Alossaimi M.A., Altamimi A.S.A., Alqahtani S.M., Hassan M.Z., Rashid M., Kamal M., Afzal O HPLC Method Development and Validation for the Estimation of Thymoquinone in Nigella sativa Seed Extract by Quality by Design (QbD) Approach Latin American Journal of Pharmacy 41 6 1110-1118 2022
88 S.M. Kawish, Shwetakshi Sharma, Waleed H Almalki, Saad Alghamdi, Obaid Afzal, Imran Kazmi, Abdulmalik Saleh Alfawaz Altamimi, Fahad A. Al-Abbasi, Sarwar Beg and Farhan J Ahmad Additive Manufacturing and Printing Approaches for the Development of Pharmaceutical Dosage Forms with Improved Biopharmaceutical Attributes. Current Drug Metabolism 23 8 616 - 629 2022
89 Suman Rohilla, Mahaveer Singh, Sami I. Alzarea, Waleed Hassan Al-Malki, Fahad A. Al-Abbasi, Imran Kazmi, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Sachin Kumar Singh, Dinesh Kumar Chellappan, Kamal Dua, Gaurav Gupta Recent developments and challenges in the molecular targeted therapies of non-small cell lung cancer Journal of Environmental Pathology, Toxicology and Oncology 42 1 27-50 2022
90 Obaid Afzal, Hisham Abdulaziz Alshammari, Mohammad A. Altamimi, Afzal Hussain, Basmah Almohaywi, Abdulmalik S.A. Altamimi Hansen solubility parameters and green nanocarrier based removal of trimethoprim from contaminated aqueous solution Journal of Molecular Liquids 361 119657 2022
91 Khalid Saad Alharbi, Waleed Hassan Almalki, Sami I. Alzarea, Imran Kazmi, Fahad A. Al-Abbasi, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Sachin Kumar Singh, Kamal Dua, Gaurav Gupta A narrative review on the biology of piezo1 with platelet-rich plasma in cardiac cell regeneration Chemico-Biological Interactions 363 110011 2022
92 Aljurbui S.J., Hussain A., Yusuf M., Ramzan M., Afzal O., Almohaywi B., Yasmin S., Altamimi A.S.A. Impact of Composition and Morphology of Ketoconazole-Loaded Solid Lipid Nanoparticles on Intestinal Permeation and Gastroplus-Based Prediction Studies ACS Omega 7 26 22406–22420 2022
93 Khalid Saad Alharbi, Tabinda Ali, Yogendra Singh, Ahmed Saleh Ali Al-Ghamdi, Imran Kazmi, Fahad A. Al-Abbasi, Sami I. Alzarea, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Sachin Kumar Singh, Dinesh Kumar Chellappan, Kamal Dua, Gaurav Gupta Biochemical interaction of pyrvinium in gentamicin-induced acute kidney injury by modulating calcium dyshomeostasis and mitochondrial dysfunction Chemico-Biological Interactions 363 110020 2022
94 Madhu Gupta, Vikas Sharma, Kalicharan Sharma, Anoop Kumar, Ajay Sharma, Imran Kazmi, Fahad A. Al-Abbasi, Sami I. Alzarea, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Sachin Kumar Singh, Gaurav Gupta, Keshav Raj Paudel, Philip M. Hansbro, Kamal Dua A kNGR Peptide-Tethered Lipid–Polymer Hybrid Nanocarrier-Based Synergistic Approach for Effective Tumor Therapy: Development, Characterization, Ex-Vivo, and In-Vivo Assessment Pharmaceutics 14 7 1401 2022
95 Sarwar Beg, Mayank Handa, Rahul Shukla, Mahfoozur Rahman, Waleed H. Almalki, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi Wearable smart devices in cancer diagnosis and remote clinical trial monitoring: transforming the healthcare applications Drug Discovery Today 27 10 103314 2022
96 Khalid Saad Alharbi, Navneet Joshi, Yogendra Singh, Waleed Hassan almalki, Imran Kazmi, Fahad A. Al-Abbasi, Sami I. Alzarea, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Gaurav Gupta Molecular exploration of hidden pleiotropic activities of azoles on dermatophytes in human tinea corporis infection Journal of Medical Mycology 32 4 101311 2022
97 Beg M.A., Shivangi, Afzal O., Akhtar M.S., Altamimi A.S.A., Hussain A., Imam M.A., Ahmad M.N., Chopra S., Athar F. Potential Efficacy of β-Amyrin Targeting Mycobacterial Universal Stress Protein by In Vitro and In Silico Approach Molecules 27 14 4581 2022
98 Shaharyar M.A., Bhowmik R., Afzal O., Altamimi A.S.A., Alzarea S.I., Almalki W.H., Ali S.Z., Mandal P., Mandal A., Ayoob M., Kazmi I., Karmakar S. Anti-Hypertensive Activity of Some Selected Unani Formulations: An Evidence-Based Approach for Verification of Traditional Unani Claims Using LC-MS/MS for the Evaluation of Clinically Relevant Blood Parameters in Laboratory Rats Journal of Clinical Medicine 11 15 4628 2022
99 Obaid Afzal, Md Habban Akhter, Irfan Ahmad, Khursheed Muzammil, Adam Dawria, Mohammad Zeyaullah, Abdulmalik SA Altamimi, Habibullah Khalilullah, Shehla Nasar Mir Najib Ullah, Mohammad Akhlaquer Rahman, Abuzer Ali, Naiyer Shahzad, Mariusz Jaremko, Abdul-Hamid Emwas, Ibrahim Abdel Aziz Ibrahim A β–Sitosterol Encapsulated Biocompatible Alginate/Chitosan Polymer Nanocomposite for the Treatment of Breast Cancer Pharmaceutics 14 8 1711 2022
100 Khalid Saad Alharbi, Mohammad Arshad Javed Shaikh, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Waleed Hassan Almalki, Sami I. Alzarea, Imran Kazmi, Fahad A. Al-Abbasi, Sachin Kumar Singh, Kamal Dua, Gaurav Gupta An overview of epithelial growth factor receptor (EGFR) inhibitors in cancer therapy Chemico-Biological Interactions 366 110108 2022
101 Debjyoti Talukdar, Parveen Kumar, Deepak Sharma, Vishal M Balaramnavar, Imran Kazmi, Fahad A. Al-Abbasi, Sami I. Alzarea, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Gaurav Gupta, Madan Mohan Gupta Anti-Cancer Phytochemical-Based Nano-Formulations: Therapeutic Intervention in Cancer Cell Lines Journal of Environmental Pathology, Toxicology and Oncology 42 1 79-93 2022
102 Manali Singh, Sanjeev Agrawal, Obaid Afzal, Abdulmalik S. A. Altamimi, Alya Redhwan, Nawaf Alshammari, Mitesh Patel, Mohd Adnan, Abdelbaset Mohamed Elasbali, Shahanavaj Khan Optimization of Elicitation Conditions to Enhance the Production of Potent Metabolite Withanolide from Withania somnifera (L.) Metabolites 12 9 854 2022
103 Khalid Saad Alharbi, Yogendra Singh, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Imran Kazmi, Fahad A. Al-Abbasi, Sami I. Alzarea, Dinesh Kumar Chellappan, Sachin Kumar Singh, Kamal Dua & Gaurav Gupta Molecular explanation of Wnt/βcatenin antagonist pyrvinium mediated calcium equilibrium changes in aging cardiovascular disorders Molecular Biology Reports 49 11 11101–11111 2022
104 Khalid Saad Alharbi, Fahad A. Al-Abbasi, Sami I. Alzarea, Obaid Afzal, Abdulmalik S. A. Altamimi, Waleed Hassan Almalki, Muhammad Shahid Nadeem, Muhammad Afzal, Nadeem Sayyed, Imran Kazmi Effects of the Anthocyanin Hirsutidin on Gastric Ulcers: Improved Healing through Antioxidant Mechanisms Journal of Natural Products 85 10 2406–2412 2022
105 Mohamed Jawed Ahsan, Amena Ali, Abuzer Ali, Arunkumar Thiriveedhi, Mohammed A. Bakht, Mohammad Yusuf, Salahuddin, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi Pyrazoline Containing Compounds as Therapeutic Targets for Neurodegenerative Disorders ACS Omega
7 43 38207–38245 2022
106 Obaid Afzal, Mohammad Yusuf, Mohamed Jawed Ahsan, Abdulmalik Saleh Alfawaz Altamimi, Md. Afroz Bakht, Amena Ali, Salahuddin Chemical Modification of Curcumin into Its Semi-Synthetic Analogs Bearing Pyrimidinone Moiety as Anticancer Agents Plants
11 20 2737 2022
107 Obaid Afzal, Abdulmalik S. A. Altamimi, Bismillah Mubeen, Sami I. Alzarea, Waleed Hassan Almalki, Salwa D. Al-Qahtani, Eman M. Atiya, Fahad A. Al-Abbasi, Fatima Ali, Inam Ullah, Muhammad Shahid Nadeem, Imran Kazmi mTOR as a Potential Target for the Treatment of Microbial Infections, Inflammatory Bowel Diseases, and Colorectal Cancer International Journal of Molecular Sciences
23 20 12470 2022
108 Khalid Saad Alharbi, Mohammad Arshad Javed Shaikh, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Imran Kazmi, Fahad A Al-Abbasi, Sami I Alzarea, M Ravindra Babu, Sachin Kumar Singh, Dinesh Kumar Chellappan, Kamal Dua, Gaurav Gupta Oligonucleotides: A novel area of interest for drug delivery in neurodegenerative diseases Journal of Drug Delivery Science and Technology 77 103849 2022
109 Huan Li, Jian Li, Juanli Wang, Obaid Afzal, Abdulmalik SA Altamimi, Shehla Nasar Mir Najib Ullah, Sireen Abdul Rahim Shilbayeh, Alnada Abdalla Ibrahim, Shahanavaj Khan Analysis of Anti-Arrhythmic Impacts of Crocin through Estimation of Expression of Cx43 in Myocardial Infarction Using a Rat Animal Model ACS Omega 7 42 37164–37169 2022
110 Pankaj Kumar, Bharti Mangla, Sarwar Beg, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Waleed H. Almalki, Shehla Nasar Mir Najib Ullah, Geeta Aggarwal Optimization and validation of stability indicating RP-HPLC method for the quantification of gefitinib in bulk drug and nanoformulations: An application towards in vitro and ex vivo performance evaluation Arabian Journal of Chemistry 15 12 104333 2022
111 Asma B. Omer, Mahmood Hassan Dalhat, Mohammad Kaleem Khan, Obaid Afzal, Abdulmalik S. A. Altamimi, Sami I. Alzarea, Waleed Hassan Almalki, Imran Kazmi Butin Mitigates Memory Impairment in Streptozotocin-Induced Diabetic Rats by Inhibiting Oxidative Stress and Inflammatory Responses Metabolites 12 11 1050 2022
112 Obaid Afzal, Mahmood Hassan Dalhat, Abdulmalik S. A. Altamimi, Rabia Rasool, Sami I. Alzarea, Waleed Hassan Almalki, Bibi Nazia Murtaza, Saima Iftikhar, Shamaila Nadeem, Muhammad Shahid Nadeem, Imran Kazmi Green tea Catechins Attenuate Neurodegenerative Diseases and Cognitive Deficits Molecules 27 21 7604 2022
113 Mahfoozur Rahman, Waleed H. Almalki, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Shehla Nasar Mir Najib Ullah, Md. Abul Barkat, Sarwar Beg Chiral-engineered supraparticles: Emerging tools for drug delivery Drug Discovery Today 28 1 103420 2023
114 Barkat A., Rahman M., Alharbi K.S., Altowayan W.M., Alrobaian M., Afzal O., Altamimi A.S.A., Alhodieb F.S., Almalki W.H., Choudhry H., Singh T., Beg S. Biocompatible Polymeric Nanoparticles for Effective Codelivery of Tamoxifen with Ganoderic Acid A: Systematic Approach for Improved Breast Cancer Therapeutics Journal of Cluster Science 2022
115 Md Sayeed Akhtar, Md Quamrul Hassan, Obaid Afzal, Abdulmalik S A Altamimi, Mohd Zaheen Hassan, Arun Kumar, Asif Ansari Shaik Mohammad, Fauzia Tabassum Comparative efficacy of levosimendan, ramipril, and sacubitril/valsartan in isoproterenol induced experimental heart failure: a hemodynamic and molecular approach. Current Molecular Pharmacology 2022
116 Khalid Saad Alharbi, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Waleed Hassan Almalki, Imran Kazmi, Fahad A. Al-Abbasi, Sami I. Alzarea, Hafiz A. Makeen, Mohammed Albratty Potential role of nutraceuticals via targeting a Wnt/β-catenin and NF-κB pathway in treatment of osteoarthritis. Journal of Food Biochemistry e14427 2022
117 Mahfoozur Rahman, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Majed Alrobaian, Md. Abul Barkat, Shehla Nasar Mir Najib Ullah, Waleed H. Almalki, Tanuja Singh, Sarwar Beg, Hani Choudhry Paclitaxel and Curcumin as Dual-Drug-Loaded Lipid Nanocapsules in the Management of Brain Tumour Journal of Cluster Science 2022
118 Md Sayeed Akhtar, Md Quamrul Hassan, Aisha Siddiqui, Sirajudeen S Alavudeen, Obaid Afzal, Abdulmalik SA Altamimi, Syed Obaidur Rahman, Mallika Khurana, Mohamed Jawed Ahsan, Arun Kumar, Fauzia Tabassum Levosimendan: mechanistic insight and its diverse future aspects in cardiac care Acta Cardiologica 2022
119 Benu Chaudhary, Deepak Singla, Preeti Arya, Abhishek Dabra, Parveen Kumar, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Sami I. Alzarea, Imran Kazmi, Fahad A. Al-Abbasi, Gaurav Gupta, Madan Mohan Gupta Versatile Imidazole Synthesis Via Multicomponent Reaction Approach Journal of Heterocyclic Chemistry 2022
120 Khalid Saad Alharbi, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Waleed Hassan Almalki, Imran Kazmi, Fahad A. Al-Abbasi, Sami I. Alzarea, Hafiz A. Makeen, Mohammed Albratty A study of the molecular mechanism of quercetin and dasatinib combination as senolytic in alleviating age-related and kidney diseases Journal of Food Biochemistry e14471 2022
121 Afzal Hussain, Obaid Afzal, Mohammad A Altamimi, Abdulmalik Saleh Alfawaz Altamimi, Mohhammad Ramzan, Mohd Zaheen Hassan, Wael A Mahdi, Thomas J Webster Improved Subcutaneous Delivery of Ketoconazole Using EpiDerm and HSPiP Software-Based Simulations as Assessed by Cell Viability, Cellular Uptake, Permeation, and Hemolysis In Vitro Studies ACS Omega 2022
122 Rajeshwar Kamal Kant Arya, Juyal Vijay, Dheeraj Bisht, Mohammad Rashid, Abdulmalik Saleh Alfawaz Altamimi, Obaid Afzal, Neeraj Kumar Sethiya Enhanced Brain Delivery via Intranasal Administration of Carbamazepine Loaded Solid Lipid Nanoparticles: Optimization, Pharmacokinetic analysis, In-vitro and In-vivo Drug Release Study. Current Drug Delivery 2022

Prof.Abdulmalik Saleh Alfawaz Altamimi

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Prof.Abdulmalik Saleh Alfawaz Altamimi

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