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  2. Faculty Members /

Dr.AYMAN IBRAHIM MOHAMED GEDAWY

MD, MSc, PhD Assistant Professor Department of Basic Medical Sciences College of Medicine In Al Karj
  • AL-Kharj
  • 011-588-6166
  • a.gedawy@psau.edu.sa
  • Curriculum Vitae
  • Publications

Education

  • Degrees & Qualifications • Bachelor degree of Medicine and Surgery (M.B.B.Ch.) (December, 1999): Faculty of Medicine, Minia University, Egypt. • Master Degree (M.Sc.) in basic medical science (Pharmacology) (January, 2006): Pharmacology Dept., Faculty of Medicine, Minia University, Egypt. • PhD in Pharmacology (March, 2012): Shiga University of Medical Science, Japan.

Research Interests

  • Medicine
  • Clinical Pharmacology & Therapeutics
  • Drugs for Hepatic Diseases
  • Cardiovascular Pharmacology

Experience

  • 2016 - until now - Assistant Professor - College of Medicine, PSAU

Responsibilities

  • • Coordinator of the Foundation of Integrated Medical Science (FIMS) Block for second year medical students at Faculty of Medicine, Prince Sattam Bin Abdul-Aziz University, KSA. • Co-cordinator for the Cardiovasular Block for second year medical students at Faculty of Medicine, Prince Sattam Bin Abdul-Aziz University, KSA. • Providing Pharmacology teaching activities across all other modules of the Integrated Basic Medical Science curriculum, for medical students at Faculty of Medicine, Prince Sattam Bin Abdul-Aziz University, KSA. • I am working as Pharmacology course instructor of Clinical Pharmacology for fourth year medical students at Faculty of Medicine, Prince Sattam Bin Abdul-Aziz University, KSA. Being interested in my career as a Medical Pharmacology staff member, I have participated in education process and performing research related to Pharmacology for around 20 years getting experience in this field by working with honored Professors and colleagues in Minia University (Egypt), in Shiga University of Medical Science (Japan) and in Prince Sattam Bin AbdulAziz University, (KSA). • Peer Reviewer of manuscripts in the medical research with particular interest in Pharmacology, Toxicology and Hepatology.

Publications

  • Publications
  • Articles
  • 1. Geddawy, A., Alajmi, M., Alaskar, A.M., Alwadani, S.T., Alanezi, A.F., Alhomaidhi, A.A. and Al-Ghamdi, S., 2021. Undergraduate health sciences students’ response regarding COVID-19 pandemic in Saudi Arabia: an observational study. Postgraduate Medicine. DOI: 10.1080/00325481.2021.2017184.
  • 2. Gunasekaran, S., Mayakrishnan, V., Al-Ghamdi, S., Alsaidan, M., Geddawy, A., Abdelaziz, M.A., Mohideen, A.P., Bahakim, N.O., Ramesh, T. and Ayyakannu, U.R.N., 2021. Investigation of phytochemical profile and in vivo anti-proliferative effect of Laetiporus versisporus (Lloyd) Imazeki mushroom against diethylnitrosamine-induced hepatocellular carcinoma. Journal of King Saud University–Science, 33, p.101551.
  • 3. Sureka, C., Elango, V., Al-Ghamdi, S., Aldossari, K. K., Alsaidan, M., Geddawy, A., Abdelaziz, M. A., Mohideen, A. P., & Ramesh, T. (2021). Ameliorative property of Sesbania grandiflora on carbohydrate metabolic enzymes in the liver and kidney of streptozotocin-induced diabetic rats. Saudi journal of biological sciences, 28(7), 3669–3677. https://doi.org/10.1016/j.sjbs.2021.05.002
  • 4. Bahakim, N.O., Geddawy, A., Sharma, K., Alkhathlan, K.M., Alsheddi, M.I.M., Al-Zogbi, A.S.A., Alonazi, A.S., Alzahrani, M.G., Albassam, K.A.M. and Al-Ghamdi, S. Visual status among undergraduate students: Findings from an emerging university in Saudi Arabia. Saudi Journal of Biological Sciences. 2021.
  • 5. Balaha M, Ahmed N, Geddawy A, Kandeel S. Fraxetin prevented sodium fluoride-induced chronic pancreatitis in rats: Role of anti-inflammatory, antioxidant, antifibrotic and anti-apoptotic activities. Int Immunopharmacol. 2021 Apr;93:107372. doi: 10.1016/j.intimp.2021.107372.
  • 6. Geddawy A, Al-Burayk AK, Almhaine AA, Al-Ayed YS, Bin-Hotan AS, Bahakim NO, Al-Ghamdi S. Response regarding the importance of vitamin D and calcium among undergraduate health sciences students in Al Kharj, Saudi Arabia. Arch Osteoporos. 2020 Jul 23;15(1):114. doi: 10.1007/s11657-020-00790-9.
  • 7. Seham A. Abdel-Gaber, Ayman Geddawy, Rabab A. Moussa. The Hepatoprotective Effect of Sitagliptin against Hepatic Ischemia Reperfusion-induced Injury in Rats involves Nrf-2/HO-1 Pathway. Pharmacological Report. 2019; 71: 104 4-1049.
  • 8. Ibrahim MA, Geddawy A, Abdel-Wahab S. Sitagliptin prevents isoproterenol-induced myocardial infarction in rats by modulating nitric oxide synthase enzymes. European Journal of Pharmacology. 2018; 829: 63-69.
  • 9. Abdel-Aziz A, Ibrahim MA, El-Shiekh AA, Osman NA, Geddawy A, Abdelrahman A. Prophylactic Effect of Diacerein against Cisplatin-Induced Nephrotoxicity in Rats. International Journal of Pharmacology. 2018; 14(3) 384-90.
  • 10. Geddawy A, Elbahie NM, Ibrahim YF, Ibrahim MA. Direct acting anti-hepatitis C virus drugs: clinical pharmacology and future direction. Journal of Translational Internal Medicine. 2017; 5 (1), 8-17.
  • 11. Geddawy A, Hussian M, Kamel MY, Kamal R, Ibrahim MA. Effects of Liraglutide and Vitamin E in Fructose-Induced Metabolic Syndrome in Rats. Pharmacology. 2017;99(1-2):48-56.
  • 12. Tawa M, Geddawy A, Shimosato T, Iwasaki H, Imamura T, Okamura T. Soluble guanylate cyclase redox state under hypoxia or hypoxia/reoxygenation in isolated monkey coronary arteries. Journal of Pharmacological Science. 2014;125(2): 169-75.
  • 13. Okamura T, Tawa M, Geddawy A, Shimosato T, Iwasaki H, Shintaku H, Yoshida Y, Masada M, Shinozaki K, Imamura T. Effects of atorvastatin, amlodipine, and their combination on vascular dysfunction in insulin-resistant rats. Journal of Pharmacological Science. 2014;124(1):76-85.
  • 14. Ibrahim MA, Kelleni M, Geddawy A. Nonalcoholic fatty liver disease: current and potential therapies. Life Sciences. 2013; 92(2): 114-8.
  • 15. Shimosato T, Geddawy A, Tawa M, Imamura T, Ayajiki K, Okamura T. Chronic administration of nicotine-free cigarette smoke extract impaired endothelium-dependent vascular relaxation in rats via increased vascular oxidative stress. Journal of Pharmacological Science. 2012;118(2):206-14.
  • 16. Tawa M, Yamamizu K, Geddawy A, Shimosato T, Imamura T, Ayajiki K, Okamura T. Impaiment by hypoxia or hypoxia/reoxygenation of nitric oxide-meditaed relaxation in isolated monkey coronary artery: the role of intracellular superoxide. Journal of Pharmacological Science. 2011;116(2):188-196.
  • 17. Tawa M, Fukumoto T, Ohkita M, Yamashita N, Geddawy A, Imamura T, Ayajiki K, Okamura T, Matsumura Y. Contribution of Nitric Oxide in Big Endothelin-1-Induced Cardioprotective Effects on Iischemia/Reperfusion Injury in Rat Hearts. Journal of Cardiovascular Pharmacology. 2011;57(5): 575-578.
  • 18. Tawa M, Fukumoto T, Ohkita M, Yamashita N, Geddawy A, Imamura T, Ayajiki K, Okamura T, Matsumura Y. Effects of Exogenous Big Endothelin-1 on Postischemic Cardiac Dysfunction and Norepinephrine Overflow in Rat Hearts. Hypertension Research. 2011;34(2): 218-224.
  • 19. Geddawy A, Shimosato T, Tawa M, Imamura T, Okamura T. Mechanism Underlying Endothelium-Dependent Relaxation by 2-Methylthio-ADP in Monkey Cerebral Artery. Journal of Pharmacological Science. 2010;114: 180–188.
  • 20. Geddawy A, Shimosato T, Tawa M, Imamura T, Okamura T. Comparison of Endothelium-Related Responses to Nucleotides of Dog and Monkey Cerebral Arteries. Journal of Pharmacological Science. 2010;112: 378–381.
  • Abstracts
  • • Seham A. Abdel-Gaber, Ayman Geddawy, Rabab A. Moussa (2019). The Mechanism Mediating the Effect of Dipeptidyl Peptidase-IV Inhibitor against Hepatic Injury in Rats. The BioNat-6, Egypt.
  • • Heba Hafez, Mohamed A. Ibrahim, Salwa Ibrahim, Entesar Amin, Wafaey Goma, Ayman Geddawy, Aly Abdelrahman. Effect of Hemin on Renal Toxicity induced by Methotrexate in Rats: the Role of Nitric Oxide. The 57th Scientific Meeting of the Egyptian Society of Pharmacology and Experimental Therapeutics (ESPET). Egypt (BUE), El Shorooq City, April -28, 2018.
  • • Ayman Geddawy, Mohamed A. Ibrahim. Protective effect of Sitagliptin on Isoproterenol-Induced Cardiac Injury in Rats. The 56th Scientific Meeting of the Egyptian Society of Pharmacology and Experimental Therapeutics (ESPET). Egypt (BUE), El Shorooq City, January-28, 2017.
  • • Maha Kamel, Marwa Hussein, Ayman Geddawy, Mohamed A. Ibrahim. Effects of liraglutide and vitamin E in fructose-induced metabolic disorders in rats. The 55th Annual Scientific Meeting of the Egyptian Society of Pharmacology and Experimental Therapeutics (ESPET). Egypt (BUE), El Shorooq City, March 5, 2016.
  • • Geddawy A, Tawa M, Imamura T, Okamura T. Regional Difference in the “EDHF-type” Relaxation Caused by Nucleotides in Monkey Cerebral Artery. The 34th Annual Meeting of the Japanese Society of Hypertension, Utsonomyia, October 20-22, 2011.
  • • Geddawy A, Shimosato T, Tawa M, Imamura T, Okamura T. Nucleotide-induced relaxations in monkey cerebral arteries isolated from various regions. International Conference on Purinergic Drugs and Targets - 4th Joint German-Italian Purine Club Meeting, Bonn, Germany, July 22-25, 2011.
  • • Imamura T, Tawa M, Geddawy A, Shimosato T, Okamura T. TNF receptor-1 functions as Gq-coupled receptor mediating TNF-alpha signaling to stimulate glucose transport in adipocytes. J Pharmacol Sci. 115 (Supple 1) 89p. The 84th Annual Meeting of the Japanese Pharmacological Society, Yokohama, March 22-24, 2011.
  • • Geddawy A, Shimosato T, Tawa M, Imamura T, Okamura T. Mechanism Underlying Endothelium-Dependent Relaxation by a P2Y1 agonist in Monkey Cerebral Artery. The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide, Kyoto, June 14-18, 2010.
  • • Imamura T, Tawa M, Geddawy A, Ayajiki K, Okamura T. Glycogen synthase kinase-3 beta inhibitor stimulates glucose transport in adipocytes, via the regulation of dynein motor activity. J Pharmacol Sci. 112 (Supple 1) 125p. The 83rd Annual Meeting of the Japanese Pharmacological Society, Osaka, March 16-18, 2009.
  • • Geddawy A, Shimosato T, Tawa M, Imamura T, Okamura T. Possible mechanisms underlying UTP-induced relaxation in monkey cerebral artery. The 116th Kinki Branch Annual Meeting of Japanese Pharmacological Society, Otsu, November 13, 2009.
  • • Tawa M, Yamamizu K, Geddawy A, Ayajiki K, Okamura T. Hypoxia- and/or reoxygenation induced deterioration of vascular smooth muscle. The 9th Annual Meeting of the Japanese NO Society, Shizuoka, May 8-9, 2009.
  • • Tawa M, Yamamizu K, Geddawy A, Imamura T, Ayajiki K, Okamura T. Hypoxia- or hypoxia/reoxygenation-induced deterioration of vascular smooth muscle function: the role of intracellular superoxide. J Pharmacol Sci. 109 (Supple 1) 113p. The 82nd Annual Meeting of the Japanese Pharmacological Society, Yokohama, March 16-18, 2009.
  • • Ayajiki K, Tawa M, Geddawy A, Okamura T. Effect of cilostazol on the response to perivascular nerve stimulation. The 31st Annual Meeting of the Japanese Society of Hypertension, Sapporo, October 9-11, 2008.

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