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Dr.ALI IBRAHIM YAHYA ALTHARAWI

PhD in Pharmaceutical and Biomedical Science Associate Professor Department of Pharmaceutical Chemistry College of Pharmacy AL-Kharj
  • Kharj
  • 011-588-8888
  • a.altharawi@psau.edu.sa
  • Curriculum Vitae
  • Publications

Education

  • BSc. of Pharmacy with 2nd-Class Honor, King Saud University (2009). MSc. of Pharmaceutical and Biomedical Science, Georgia University - USA (2013). PhD. of Pharmaceutical science, King's College London - UK (2019).

Research Interests

  • Design and synthesis of Anticancer and Antimalarial Therapeutics.
  • Applications of Vibrational Spectroscopy to Study Live Cells.

Experience

  • 2017 - 2018 - Research Investigator - King's College London and Reims University
  • 2013 - 2015 - Lecturer - PSAU
  • 2008 - 2009 - Inpatient Pharmacist - NGHA

Responsibilities

  • Supervisor of Alumni Unit at Faculty of Pharmacy.

Publications

  • An eco- friendly, selective, and sensitive spectrofluorimetric method for the quantification of Dolutegravir in its bulk and tablet dosage form, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy (2022).
  • Novel and Potential Small Molecule Scaffolds as DYRK1A Inhibitors by Integrated Molecular Docking-Based Virtual Screening and Dynamics Simulation Study, Molecules (2022).
  • Illuminating Host-Parasite Interaction at the Cellular and Subcellular Levels with Infrared Microspectroscopy, Cells (2022).
  • In vitro Fourier transform infrared spectroscopic study of the effect of glycerol on the uptake of beclomethasone dipropionate in living respiratory cells, International journal of Pharmaceutics (2021).
  • Evaluation of Haloxylon Persicum Leaves Ethanolic Extract for Phytochemical, Antioxidant, Anticancer, and Antimicrobial Properties, Current Topics In Nutraceutical Research (2021).
  • Structural insight into the binding pattern and interaction mechanism of chemotherapeutic agents with Sorcin by docking and molecular dynamic simulation, Colloids and Surfaces B: Biointerfaces (2021).
  • Synthesis, Anticancer Screening of Some Novel Trimethoxy Quinazolines and VEGFR2, EGFR Tyrosine Kinase Inhibitors Assay; Molecular Docking Studies, Molecules (2021).
  • Synthesis, characterization, biological evaluation and molecular docking of a new quinazolinone-based derivative as a potent dual inhibitor for VEGFR-2 and EGFR tyrosine kinases, Journal of Biomolecular Structure and Dynamics (2021).
  • Identifying the Responses from the Estrogen Receptor-Expressed MCF7 Cells Treated in Anticancer Drugs of Different Modes of Action Using Live-Cell FTIR Spectroscopy, ACS Omega (2020).
  • Structure-based virtual screening and molecular dynamics of phytochemicals derived from Saudi medicinal plants to identify potential COVID-19 therapeutics, Arabian Journal of Chemistry (2020).
  • Synchrotron Photothermal Infrared Nanospectroscopy of Drug-Induced Phospholipidosis in Macrophages, Analytical Chemistry (2020).
  • Tracking glycosylation in live cells using FTIR spectroscopy, Talanta (2020).
  • Transmission Fourier Transform Infrared Spectroscopic Imaging, Mapping, and Synchrotron Scanning Microscopy with Zinc Sulfide Hemispheres on Living Mammalian Cells at Sub-Cellular Resolution, Applied Spectroscopy (2020).
  • Towards identifying the mode of action of drugs using live-cell FTIR spectroscopy, The Analyst (2019)
  • In situ Fourier transform infrared analysis of live cells' response to doxorubicin, Biochimica et Biophysica Acta - Molecular Cell Research (2015).
  • 1,4-naphthoquinone cations as antiplasmodial agents: Hydroxy-, acyloxy-, and alkoxy-substituted analogues, ACS Medicinal Chemistry Letters (2012).
  • Phase-transfer catalysts in the O-alkylation of 2-hydroxynaphthoquinones, Synthesis (2012).

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