أعضاء هيئة التدريس | مواقع أعضاء هيئة التدريس

د.منال عبدالله مهدي العصيمي

دكتوراه و ماجستير في الكيمياء الصيدلية التحليلية من جامعة ستراثكلايدبالمملكةالمتحدة. استشاري صيدلي.الهيئةالسعوديةللتخصصات الصحية استاذ مساعد قسم الكيمياء الصيدلية كلية الصيدلة بالخرج

الخرج
011-588-6847
m.alossaimi@psau.edu.sa

السيرة الذاتية
الأبحاث العلمية

المؤهلات العلمية

PhD of Pharmaceutical analytical chemistry - University of Strathclyde -UK
MSc of Pharmaceutical analysis - University of Strathclyde -UK
Bachelor of Pharmacy- King Saud University - Saudi Arabia

الاهتمامات البحثية

• Biosimilar and biological drugs analysis and comparability.
• Pharmaceutical analysis and bioanalytical.
• Metabolomics.
• In vivo and In vitro research.
• Drug discovery.
• Optimization and validation of analytical methods.

الخبرات

2020 - حتى الآن - A vice head of pharmaceutical chemistry department - PSAU
2018 - 2020 - A Head of Academic Advising Unit - PSAU
2016 - 2018 - Supervisor of scientific research, technical and advisory committees - MOH
2003 - 2008 - Analytical Pharmacist - MOH

الأبحاث العلمية

1. Alossaimi, M.A., El-Gamal, R.M., Altharawi, A. and Abbas, M., 2022. An Eco-Friendly, Selective, and Sensitive Spectrofluorimetric Method for the Quantification of Dolutegravir in its Bulk and Tablet Dosage Form. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, p.121035.
2. BISHT A., NEGI N., ASIF M., KAMAL M., ALOSSAIMI M. A., RIADIMi Y., 2022, crowave-assisted Synthesis, Characterization, and Evaluation of Maleimide and Phthalimide Derivatives as an Antioxidant Agent. Lat. Am. J. Pharm. 41 (3).
3. Kiran S., PASHA T., ASIF M., KAMAL M., JAWAID T., ALOSSAIMI M.A., Ramesh B., MAJUMDER, 2022, Development and Validation of a Reverse Phase-High Performance Liquid Chromatography (RP-HPLC) Methods for Atenolol Using Quality by Design (QbD) Approaches. Lat. Am. J. Pharm. 41 (3).
4. Yusuf M., Asif M., Kamal M., Jawaid T., Alossaimi M. A., Sharma M. , Ansar N., 2022, In Silico Molecular Studies and Synthesis of Some Pyridazinone Scaffolds as Anti-proliferative Agents. Indian Journal of Heterocyclic Chemistry, 32(…), p.1-15.
5. Alqahtani, S.M., Altharawi A., Alabbas, A.B., Alossaimi, M.A. Kamal M., Alasmary F. A., Alamri M. A., 2022. Evaluation of haloxylon persicum leaves ethanolic extract: phytochemical, antioxidant, anticancer and antimicrobial studies.
6. Shahroz, M.M., Sharma, H.K., Altamimi, A.S., Alamri, M.A., Ali, A., Ali, A., Alqahtani, S., Altharawi, A., Alabbas, A.B., Alossaimi, M.A. and Riadi, Y., 2022. Novel and Potential Small Molecule Scaffolds as DYRK1A Inhibitors by Integrated Molecular Docking-Based Virtual Screening and Dynamics Simulation Study. Molecules, 27(4), p.1159.
7. Rahman, M., Afzal, O., Panda, S.K., Kazmi, I., Ali, A.M.A., Alossaimi, M.A., Al-Abbasi, F.A., Almalki, W.H., Katouah, H.A., Kumar, V. and Barkat, M.A., 2021. UPLC–MS/MS Method Validation for Estimation of Resveratrol in Rat Skin from Liposphere Gel Formulation and Its Application to Dermatokinetic Studies in Rats. Journal of Chromatographic Science.
8. Alrobaian, M., Panda, S.S., Almalki, W.H., Afzal, O., Kazmi, I., Alossaimi, M.A., Al-Abbasi, F.A., Katouah, H.A., Rub, R.A., Kumar, B.V.V. and Rahman, M., 2021. Development and Validation of Chemometrics-Assisted Green UPLC-MS/MS Bioanalytical Method for Simultaneous Estimation of Capecitabine and Lapatinib in Rat Plasma. Journal of Chromatographic Science.
9. Alrobaian, M., Panda, S.S., Afzal, O., Kazmi, I., Alossaimi, M.A., Al-Abbasi, F.A., Almalki, W.H., Soni, K., Alam, O., Alam, M.N. and Rub, R.A., 2021. Development of a Validated Bioanalytical UPLC–MS/MS Method for Quantification of Neratinib: A Recent Application to Pharmacokinetic Studies in Rat Plasma. Journal of Chromatographic Science.
10. Hussain, A., Alshehri, S., Ramzan, M., Afzal, O., Altamimi, A.S. and Alossaimi, M.A., 2021. Biocompatible solvent selection based on thermodynamic and computational solubility models, in-silico GastroPlus prediction, and cellular studies of ketoconazole for subcutaneous delivery. Journal of Drug Delivery Science and Technology, 65, p.102699.
11. Altamimi, A.S., El-Azab, A.S., Abdelhamid, S.G., Alamri, M.A., Bayoumi, A.H., Alqahtani, S.M., Alabbas, A.B., Altharawi, A.I., Alossaimi, M.A. and Mohamed, M.A., 2021. Synthesis, Anticancer Screening of Some Novel Trimethoxy Quinazolines and VEGFR2, EGFR Tyrosine Kinase Inhibitors Assay; Molecular Docking Studies. Molecules, 26(10), p.2992.
12. Alahmari, A.K., Almalki, Z.S., Iqbal, M.S., Alossaimi, M.A., Alsaber, M.Z., Alanazi, R.A., Alruwaili, Y.M., Altheiby, S.N. and Salman, T.O.B., 2021. Knowledge and attitude of pharmacists about biosimilar medications in Saudi Arabia. International Journal of Pharmaceutical Investigation, 11(1), pp.123-126.
13. Riadi, Y., Alamri, M.A., Geesi, M.H., Anouar, E.H., Ouerghi, O., Alabbas, A.B., Alossaimi, M.A., Altharawi, A., Dehbi, O. and Alqahtani, S.M., 2021. Synthesis, characterization, biological evaluation and molecular docking of a new quinazolinone-based derivative as a potent dual inhibitor for VEGFR-2 and EGFR tyrosine kinases. Journal of Biomolecular Structure and Dynamics, pp.1-7.
14. Almalki, Z.S., Iqbal, M.S., Alossaimi, M.A., Lasaf, A.M., Almawash, B.A., Aldossary, F.H., Marghalani, A.M. and Alsubaihi, Y.A., 2020. Physicians’ Knowledge and Awareness about Biosimilars in Saudi Arabia: What is Imperative to Know??. Journal of Young Pharmacists, 12(3), p.280.
15. Ziyad S. Almalki, Muhammad Shahid Iqbal, Manal A. Alossaimi, Mohammed Zaid Alsaber, Raslan Abdullah Alanazi, Yazeed Mohammed Alruwaili, Saad Nashmi Altheiby, Thekra Omar Bin Salman, Pharmacists' Awareness and Perceptions of Biosimilars in Saudi Arabia, Asian Journal of Pharmaceutics, Sep 2020, 14 (3).
16. Alamri, M.A., Altharawi, A., Alabbas, A.B., Alossaimi, M.A. and Alqahtani, S.M., 2020. Structure-based virtual screening and molecular dynamics of phytochemicals derived from Saudi medicinal plants to identify potential COVID-19 therapeutics. Arabian Journal of Chemistry, 13(9), pp.7224-7234.
17. Alwashih, M.A., Watson, D.G., Andrew, R., Stimson, R.H., Alossaimi, M., Blackburn, G. and Walker, B.R., 2017. Plasma metabolomic profile varies with glucocorticoid dose in patients with congenital adrenal hyperplasia. Scientific Reports, 7(1), pp.1-7.
18. Maher, H.M., Alzoman, N.Z., Alshehri, M.M., Aljohar, H.I., Shehata, S., Alossaimi, M. and Abanmy, N.O., 2015. Simultaneous determination of dexamethasone and lenalidomide in rat plasma by solid phase extraction and ultra-performance liquid chromatography-tandem mass spectrometry: application to pharmacokinetic studies. RSC advances, 5(119), pp.98600-98609.
19. Tonelli, F., Alossaimi, M., Natarajan, V., Gorshkova, I., Berdyshev, E., Bittman, R., Watson, D.G., Pyne, S. and Pyne, N.J., 2013. The roles of sphingosine kinase 1 and 2 in regulating the metabolome and survival of prostate cancer cells. Biomolecules, 3(2), pp.316-333.
20. Watson, D.G., Tonelli, F., Alossaimi, M., Williamson, L., Chan, E., Gorshkova, I., Berdyshev, E., Bittman, R., Pyne, N.J. and Pyne, S., 2013. The roles of sphingosine kinases 1 and 2 in regulating the Warburg effect in prostate cancer cells. Cellular signalling, 25(4), pp.1011-1017.
21. Tonelli, F., Alossaimi, M., Williamson, L., Tate, R.J., Watson, D.G., Chan, E., Bittman, R., Pyne, N.J. and Pyne, S., 2013. The sphingosine kinase inhibitor 2‐(p‐hyroxyanilino)‐4‐(p‐chlorophenyl) thiazole reduces androgen receptor expression via an oxidative stress‐dependent mechanism. British journal of pharmacology, 168(6), pp.1497-1505.

للاتصال من داخل الجامعة 1200
للاتصال من خارج الجامعة 011-588-1200
البريد الإلكترونى pr@psau.edu.sa
لطلب خدمة وفتح بلاغ للأعطال ithelp.psau.edu.sa

مواقع أعضاء هيئة التدريس

د.منال عبدالله مهدي العصيمي

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مواقع أعضاء هيئة التدريس

د.منال عبدالله مهدي العصيمي

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