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د.فيديا ديفانتديسكان فيديا سيشادري

أستاذ مشارك كلية الصيدلة بالخرج

الخرج
011-588-6821
v.adri@psau.edu.sa

السيرة الذاتية
الأبحاث العلمية

الأبحاث العلمية

Patents:
1. Calotropisprocera extracts as anti-ulcerative colitis agents (US 9533019 B1)
The CalotropisProceraextracts as anti-ulcerative colitis agents include extracts of Calotropisproceraobtained by a method comprising the following steps: (a) providing a plant material derived from Calotropisprocera, (b) drying the plant material, (c) pulverizing the plant material to provide a fine powder; and (d) extracting the plant material by percolation using 95% aqueous alcohol in a container to obtain an alcoholic extract. A method of treating ulcerative colitis comprises administering a therapeutically effective amount of an alcoholicextract of C. procerato a patient in need thereof.
Publication number US9533019 B1
Publication type Grant
Application number US 15/059,261
Publication date 3 Jan 2017
Inventors AmaniShafeekAwaad, 4 More »
Original Assignee King Saud University
Export Citation BiBTeX, EndNote, RefMan
Patent Citations (5), Non-Patent Citations (1), Classifications (5),
Legal Events (1)
External Links: USPTO, USPTO Assignment, Espacenet
2. Method of treating hypertension
10/12/17 - 20170290871 - A method of treating hypertension can include administering to a patient in need thereof a therapeutically effective amount of an extract of Matricariachamomilla L. The extract can be administered orally to the patient in an amount of about 100 mg/kg to about 200 mg/kg.
Inventors:AmaniShafeekAwaad, Ghada Mohamed Zain, Reham M. El-meligy, Amal Ahmed Safhi, VidyaDevenathadesikanSeshadri, Shekhah Saud Almoqren, Nourah Ahmed An Qurain
Chapters:
1. Arun Kumar Ramu, Ranjani Rajendran, Azhagu Madhavan Sivalingam, V.D. Seshadri, Abdul Bakrudeen Ali Ahmed,
Chapter 32 - Anticancer potentiated bioactive compounds from marine flora,
Editor(s): Se-Kwon Kim, Kyung-Hoon Shin, Jayachandran Venkatesan,
Marine Antioxidants, Academic Press, 2023, Pages 421-432, ISBN 9780323950862, https://doi.org/10.1016/B978-0-323-95086-2.00021-7.
2. Ahmed, A.B.A., Adel, M., Talati, A., Lobo, V., Seshadri, V.D. (2021). Effect of Biochar Addition to Soil on Plant Quality. In: Gothandam, K.M., Ranjan, S., Dasgupta, N., Lichtfouse, E. (eds) Environmental Biotechnology Vol. 3. Environmental Chemistry for a Sustainable World, vol 50. Springer, Cham. https://doi.org/10.1007/978-3-030-48973-1_9
Research Publications:
1. Abdelsalam, S. A., Renu, K., Zahra, H. A., Abdallah, B. M., Ali, E. M., Veeraraghavan, V. P., Sivalingam, K., Ronsard, L., Ammar, R. B., Vidya, D. S., Karuppaiya, P., Al-Ramadan, S. Y., & Rajendran, P. (2023). Polyphenols Mediate Neuroprotection in Cerebral Ischemic Stroke-An Update. Nutrients, 15(5), 1107. https://doi.org/10.3390/nu15051107(Impact Factor: 5.717).
2. Zaki, R. M., Seshadri, V. D., Mutayran, A. S., Elsawaf, L. A., Hamad, A. M., Almurshedi, A. S., Yusif, R. M., & Said, M. (2022). Wound Healing Efficacy of Rosuvastatin Transethosomal Gel, I Optimal Optimization, Histological and In Vivo Evaluation. Pharmaceutics, 14(11), 2521. https://doi.org/10.3390/pharmaceutics14112521 (Impact Factor: 6.51)
3. Li, Z., Geng, Y., Wu, Q., Jin, X., Seshadri, V. D., & Liu, H. (2023). Triptonide, a Diterpenoid Displayed Anti-Inflammation, Antinociceptive, and Anti-Asthmatic Efficacy in Ovalbumin-Induced Mouse Model. Applied biochemistry and biotechnology, 195(3), 1736–1751. https://doi.org/10.1007/s12010-022-04167-1 (Impact Factor: 2.431)
4. Zaki, R. M., Alfadhel, M., DevanathaDesikan Seshadri, V., Albagami, F., Alrobaian, M., Tawati, S. M., Warsi, M. H., & Almurshedi, A. S. (2023). Fabrication and characterization of orodispersible films loaded with solid dispersion to enhance Rosuvastatin calcium bioavailability. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 31(1), 135–146. https://doi.org/10.1016/j.jsps.2022.11.012 (Impact Factor: 4.652)
5. Wu, Y., Wang, X., Li, J., Ma, H., Seshadri, V. D., & Wang, X. (2023). Benzo(A)Pyrene-Induced Lung Cancer: Chemo Protective Effect of Coronarin D in Swiss Albino Mice. Applied biochemistry and biotechnology, 195(2), 1122–1135. https://doi.org/10.1007/s12010-022-04166-2 (Impact Factor: 2.431)
6. Guo, H., Zhang, Q., Li, R., & Seshadri, V. D. (2023). Nigericin Abrogates Maternal and Embryonic Oxidative Stress in the Streptozotocin-Induced Diabetic Pregnant Rats. Applied biochemistry and biotechnology, 195(2), 801–815. https://doi.org/10.1007/s12010-022-04100-6 (Impact Factor: 2.431)
7. Gongqian Jiang, Abubucker Peer Mohideen, Vidya Devanathadesikan Seshadri, Thamaraiselvan Rengarajan. Biosynthesized tin oxide-sodium alginate-polyethylene glycol-carvacrol nanocomposite shows anticancer activity on esophagus squamous carcinoma cells,Process Biochemistry,Volume 121,2022,Pages 403-412,ISSN 1359-5113, https://doi.org/10.1016/j.procbio.2022.07.005 (Impact Factor: 4.885)
8. Zaki, R. M., Aldawsari, M. F., Alossaimi, M. A., Alzaid, S. F., Devanathadesikan Seshadri, V., Almurshedi, A. S., Aldosari, B. N., Yusif, R. M., & Sayed, O. M. (2022). Brain Targeting of Quetiapine Fumarate via Intranasal Delivery of Loaded Lipospheres: Fabrication, In-Vitro Evaluation, Optimization, and In-Vivo Assessment. Pharmaceuticals (Basel, Switzerland), 15(9), 1083. https://doi.org/10.3390/ph15091083 (Impact Factor: 5.215)
9. Seshadri, V.D., Kandasamy, K., Al Osaimi, M. et al. Stachytarpheta cayennensis-mediated copper nanoparticles shows anticancer activity in both in vitro and in vivo models. Appl Nanosci (2022). https://doi.org/10.1007/s13204-022-02546-y (Impact Factor: 3.674)
10. Zaki, R. M., Alfadhel, M. M., Alossaimi, M. A., Elsawaf, L. A., Devanathadesikan Seshadri, V., Almurshedi, A. S., Yusif, R. M., & Said, M. (2022). Central Composite Optimization of Glycerosomes for the Enhanced Oral Bioavailability and Brain Delivery of Quetiapine Fumarate. Pharmaceuticals (Basel, Switzerland), 15(8), 940. https://doi.org/10.3390/ph15080940 (Impact Factor: 5.215)
11. Zhao, J., He, B., Seshadri, V. D., & Xu, S. (2022). Anticancer Effect of Ruscogenin in B(a)P-Induced Lung Cancer in Mice via Modulation of Proinflammatory Cytokines and Mitochondrial Enzymes. Applied biochemistry and biotechnology, 194(12), 5862–5877. https://doi.org/10.1007/s12010-022-04042-z (Impact Factor: 2.431)
12. Yu, L., Liu, H., Ma, X., Seshadri, V. D., & Gao, X. (2022). Anti-atherosclerotic Effects of Myrtenal in High-Fat Diet-Induced Atherosclerosis in Rats. Applied biochemistry and biotechnology, 194(12), 5717–5733. https://doi.org/10.1007/s12010-022-04044-x (Impact Factor: 2.431)
13. Seshadri, V. D., Oyouni, A. A. A., Bawazir, W. M., Alsagaby, S. A., Alsharif, K. F., Albrakati, A., & Al-Amer, O. M. (2022). Zingiberene exerts chemopreventive activity against 7,12-dimethylbenz(a)anthracene-induced breast cancer in Sprague-Dawley rats. Journal of biochemical and molecular toxicology, 36(10), e23146. https://doi.org/10.1002/jbt.23146 (Impact Factor: 3.568)
14. Vidya Devanathadesikan Seshadri, Atif Abdulwahab A. Oyouni, Yousef M. Hawsawi, Saad Ali S. Aljohani, Osama M. Al-Amer, Waseem AlZamzami, Ahmad Hasan Mufti, Chemopreventive role of Tin oxide-Chitosan-Polyethylene glycol-Crocin nanocomposites against Lung cancer: An in vitro and in vivo approach, Process Biochemistry, Volume 120,2022,Pages 186-194,ISSN 1359-5113,https://doi.org/10.1016/j.procbio.2022.05.028. (Impact Factor: 4.885)
15. Poyil, Muhammad Musthafa, Karrar Alsharif, Mohammed H. and Seshadri, Vidya Devanathadesikan. "Anti-asthmatic activity of Saudi herbal composites from plants Bacopa monnieri and Euphorbia hirta on Guinea pigs" Green Processing and Synthesis, vol. 11, no. 1, 2022, pp. 512-525. https://doi.org/10.1515/gps-2022-0039 (Impact Factor: 4.07).
16. Seshadri, VD. Brucine promotes apoptosis in cervical cancer cells (ME-180) via suppression of inflammation and cell proliferation by regulating PI3K/AKT/mTOR signaling pathway. Environmental Toxicology, USA. 2021; 36 ( 9) : 1841 – 1847.https://doi.org/10.1002/tox.23304 (Impact Factor: 4.119).
17. Guru A, Issac PK, Saraswathi NT, Seshadri VD, Gabr GA, Arockiaraj J. Deteriorating insulin resistance due to WL15 peptide from cysteine and glycine‐rich protein 2 in high glucose‐induced rat skeletal muscle L6 cells. Cell Biology International, USA. 2021, 45 (8), 1698 – 1709. https://doi.org/10.1002/cbin.11608(Impact Factor: 3.612).
18. C Gao, Y Song, T Dou, S Jiang, H Wu, VD Seshadri, Veeraraghavan VP, P Hou. Troxerutin Abrogates Ischemic/Reperfusion-Induced Brain Injury through Ameliorating Oxidative Stress and Neuronal Inflammation by Inhibiting the Expression of NLRP3 in Sprague Dawley Rats. Journal of Environmental Pathology, Toxicology and Oncology, USA. 2021, 40 (4):11-19. https://doi.org/10.1615/JEnvironPatholToxicolOncol.2021038860 (Impact Factor: 3.567).
19. Awaad AA, El-Meligy RM, Zain GM, Safhi AA, Al Qurain NA, Almoqren SS, Zain YM, Sesh Adri VD, Al-Saikhan FI. Experimental and clinical antihypertensive activity of Matricaria chamomilla extracts and their angiotensin-converting enzyme inhibitory activity. Phytotherapy Research, USA. 2018, 32(8):1564-1573. https://doi.org/10.1002/ptr.6086 (Impact Factor: 5.878).
20. Seshadri VD. Zinc oxide nanoparticles from Cassia auriculata flowers showed the potent antimicrobial and in vitro anticancer activity against the osteosarcoma MG-63 cells. Saudi Journal of Biological Sciences, Netherlands. 2021, 28 (7): 4046 - 4054. https://doi.org/10.1016/j.sjbs.2021.04.001 (Impact Factor: 4.219).
21. Vidya Devanathadesikan Seshadri, P. Vijayaraghavan Y.-O.Kim, H.-J.Kim, Abdullah Ahmed Al-Ghamdi. Mohamed S.Elshikh, Monerah A.Al-Dosary, Qasi D.Alsubaie. In vitro antioxidant and cytotoxic activities of polyherbal extracts from Vetiveria zizanioides, Trichosanthes cucumerina, and Mollugo cerviana on HeLa and MCF-7 cell lines. Saudi Journal of Biological Sciences, Netherlands. 2020, 27 (6), 2020, 1475-148. https://doi.org/10.1016/j.sjbs.2020.04.005 (Impact Factor: 4.219).
22. Ramasamy P, Sekar S, Paramasivam S, Suri P, Chinnaiyan U, Singh R, Tanguturi Raghavaiah BP, Seshadri VD. Sulfation of chitosan from Sepia kobiensis as potential anticoagulant and antibacterial molecule. Natural Product Research, England. 2021, 1-7.https://doi.org/10.1080/14786419.2021.1956492 (Impact Factor : 2.861).
23. Pannerselvam B, Devanathadesikan V, Alagumuthu TS, Kanth SV, Pudupalayam Thangavelu K. Assessment of in-vivo biocompatibility evaluation of phytogenic gold nanoparticles on Wistar albino male rats. IET Nanobiotechnology, England. 2020. 14 (4):314-324. https://doi.org/10.1049/iet-nbt.2019.0116 (Impact Factor: 1.847).
24. Chen L, Chen J, Ramesh T, Seshadri VD, Zhu L. Zinc oxide nanoparticles from Corydalis yanhusuo attenuated the mycoplasmal pneumonia in mice through inhibiting the MAPKs signaling pathway. Microbial Pathogenesis, England. 2020.147:104270. https://doi.org/10.1016/j.micpath.2020.104270 (Impact Factor: 3.738).
25. Cui X, Wang R, Bian P, Wu Q, Seshadri VD, Liu L. Evaluation of antiarthritic activity of nimbolide against Freund's adjuvant induced arthritis in rats. Artificial Cells Nanomedicine and Biotechnology, England. 2019, 47, (1), 3391–3398. https://doi.org/10.1080/21691401.2019.1649269 (Impact Factor: 5.678).
26. Li L, Zhang W, Desikan Seshadri VD, Cao G. Synthesis and characterization of gold nanoparticles from Marsdenia tenacissima and its anticancer activity of liver cancer HepG2 cells. Artificial Cells Nanomedicine and Biotechnology, England. 2019, 47 (1), 3029 - 3036. https://doi.org/10.1080/21691401.2019.1642902 (Impact Factor: 5.678).
27. Moglad EH, Fatima F, Ahmed MM, Seshadri VD, Anwer MK, Aldawsari MF. Development of Topical Antibacterial Gel Loaded with Cefadroxil Solid Lipid Nanoparticles: In vivo Wound Healing Activity and Epithelialization Study. International Journal of Pharmacology, Pakistan. 2020, 16 (4): 298 - 309. https://doi.org/10.3923/ijp.2020.298.309 (Impact Factor: 0.751).
28. Sundararajan, B., Sathishkumar, G., Seetharaman, P. K., Moola, A. K., Duraisamy, S. M., Mutayran, A., Seshadri, V. D., Thomas, A., Ranjitha Kumari, B. D., Sivaramakrishnan, S., Kweka, E. J., & Zhou, Z. Biosynthesized Gold Nanoparticles Integrated Ointment Base for Repellent Activity Against Aedes aegypti L. Neotropical entomology, Brazil. 2021, 51(1), 151–159.https://doi.org/10.1007/s13744-021-00920-z (Impact Factor :1.33).
29. Xue J, Liu T, Liu Y, Jiang Y, Seshadri VDD, Mohan SK, Ling L. Neuroprotective effect of biosynthesised gold nanoparticles synthesised from root extract of Paeonia moutan against Parkinson disease - In vitro &In vivo model. Journal of Photochemistry and Photobiology B, Switzerland, 2019, 200, 111635. https://doi.org/10.1016/j.jphotobiol.2019.111635 (Impact Factor: 6.252).
30. Jawaid, T., Kamal, M., Singh, R., Shukla, D., Devanathadesikan, V., & Sinha, M. Anticonvulsant and neuroprotective effects of methanolic extract of Cinnamomum camphora leaves in rat brain. Oriental Pharmacy and Experimental Medicine, Singapore. 2018. 18, 237-246.https://doi.org/10.1007/s13596-018-0306-1 (Impact Factor: 0.211).
31. Ignatius V, Narayanan M, Subramanian V, Periyasamy BM. Antiulcer Activity of Indigenous Plant Operculina turpethum Linn. Journal of Evidence Based Complementary and Alternative Medicine, USA. 2013; 2013 : 272134. https://doi.org/10.1155/2013/272134 (Impact Factor: 2.629).
32. Ignatius V, Thangavel J, Tanguturi Raghavaiah BP, Sridhar MP., Sania Mohammed Eisawy Abd-El-Aal, Subramanian V and Maruthaiveeran PB(2009). Analgesic and Antipyretic activities of Operculina turpethum Linn. Silva Manso in Experimental animals. Al-Azhar Journal of Pharmaceutical sciences, Faculty of Pharmacy, Al-Azhar University, Egypt: 150 -160. (Impact Factor: ---).
33. Narayanan M, Ignatius V and T Lakshmi (2013). Antioxidant activity of berberine on benzo (A) pyrene induced experimental lung carcinogenesis in mice. Journal of Chemical and Pharmaceutical Research, India. 5(10):194-200. (Impact Factor: ---)

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