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Detection of ESAT-6 by a Label Free Miniature Immuno-Electrochemical Biosensor as a Diagnostic Tool for Tuberculosis

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Detection of ESAT-6 by a Label Free Miniature Immuno-Electrochemical Biosensor as a Diagnostic Tool for Tuberculosis

Mohamed fethi Diouani1,4*, Oussama Ouerghi3, 4*, Amira Refai 2,4, Kamel Belgacem1,4, Chaker Tlili1,4, Dhafer Laouini2,4, Makram Essafi 2,4

1Institut Pasteur de Tunis, LEVM LR11 IPT03, Tunis, 1002, Tunisia

 2 Institut Pasteur de Tunis, LTCII LR11 IPT02, Tunis, 1002, Tunisia

3 Prince Sattam Bin AbdulazizUniversity

 4Université Tunis El Manar, Tunis, 1068, Tunisia

* These authors equally contributed to this work

Abstract: Tuberculosis (TB) is a worldwide disease considered as a major health problem with high morbidity and mortality rates. Poor detection of Mycobacterium tuberculosis (Mtb), the causative agent of TB, remains a major obstacle to a global control of this disease. Here we report the development of a new test, detecting the major virulent factor...

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