يختص هذا المقرر بدراسة البكتريا الممرضة، وآلية حدوثها، وطريقة انتقالها، ودراسة وبائيتها، وكذلك طرق عزلها وزراعتها وقابليتها للمضادات الحيوية المختلفة. ومن أمثلة تلك البكتريا المكورات الهوائية موجبة الجرام، والعصيات موجبة الجرام، ميكروب الدرن، ميكروبات النيسريا المسببة للحمى الشوكية، وكذلك الميكروبات المعوية وغيرها ومعرفة طرق تشخيصها.
|Introduction: • General Characteristics of bacteria||
This introductory lecture describes about the Kingdom Bacteria, Their types, hosts, living places, General Characteristics and major types
|Taxonomy and Classification of bacteria||
This lecture speaks about the taxonomy. i.e. classification of bacteria
Bergey's manual of determinative bacteriology
Hacekel's three kingdom concept
Binomial nomenclature and its rules etc...
|Normal microbial flora of human body||
This topic describes about the commensols or normal flora of the human body- their different locations- list of normal flora- source of origin- their advantages and disadvantages.
|Host Parasite Relationship||
This topic describes about the different types of infections- definitions of host parasite relationships- Sources of infection- methods of transmission of infections-microbial pathogenecity etc..
|Mechanisms of Bacteria Pathogenecity||
This lecture focusses on the definition of viruence, pathogenecity - different types of virulence factorsin bacteria, toxins, adherence factors, capsules, pathogenecity island, etc.
|Gram Positive Bacteria- I||
This topic covers Gram Positive bacteria like Staphylococcus spp, Streptococcus spp, Neiserria Spp, Pneumococci-- Their structure, virulence factors, characters, diseases, lab diagnosis and control measures.
|Gram Positive Bacteria-II||
This topic covers Gram Postive bacteria such as Bacillus sp. , Listeria monocytogenes Erysipelothrix rhusiopathiae , Corynebacterium sp., Gardnerella vaginalis , Lactobacillus sp. Nocardia sp., Actinomyces sp., & Streptomyces- their pathogenecity, diseases and control measures.
Introduction- Classification of tubercle bacilli- disease caused- pathogenecity factors- lab diagnosis- control measures and drug resistance
About Mycobacterium leprae, virulence factors, disease caused, lab diagnopsis and treatment mesures
|Anti tuberculosis treatment||
This lecture speaks indetail about tuberculosis disease, its stages, drugs, side effects etc.
Describes about the anaerobic pathogenic bacteria- Clostridium perfringes, Clostridium botulium and Clostridium tetani- Pathogenecity- diseases- lab diagnosis and Control measures
Describes in detail about the Enterobacteriacease family, Classification, diseases causes, pathogenecity, lab diagnosis, treatment and control measures
|Emerging Bacterial Diseases||
This topic discusses about the upcoming bacteria infections
This topic delas with the non- Enterobacteriaceae family of bacteria like Pseudomonas aeruginosa and Vibrio cholerae. Its family, clinical diseases, pathogenesis, laboratory diagnosis, treatment and prevention methods.
|Haemophilus and Rickettsia||
This topic discusses about the other Gram negative bacterial groups like Haemophilus and Rickettsia spp. Its characters, pathogenecity, diseases caused, lab diagnosis, control and treatment procedures.
About Chalmydial diseases- its diagnosis and treatment measures
|Sexually transmitted bacterial diseases||
This lecure describes about the sexually transmitted bacterial diseases like Syphilis, Chlamydiosis and Gonorrhoea. Its causative agents, pathogenecity, sources, lab diagnosis, treatment and control measures.
|MLAB 471 - Clinical Bacteriology-I|
This course covers systemic pathogenic bacteria including mycoplasmal, rickettsial and chlamydial diseases of humans, their pathogenesis, modes of transmission, epidemiology, methods for isolation and identification. Areas of study include: aerobic Gram-positive cocci, bacilli and acid fast bacilli, Haemophilus, Brucella, Bortedella, Neisseria and Enterobacteriaceae, as well as methods of testing their susceptibility to antibacterial agents.
Pre-requisites for this course : General Microbiology (MLAB-352)
· Mim’s Medical Microbiology. Richard V Goreing, 4th edition (2008); Publisher: Elsevier publications
· Ananthanarayanan R and CK Jayaram Panicker, 1994, Textbook of microbiology Orient Longman
· Medical Microbiology by Murray and others. Last Edition. Publisher: Mosby
1. Microbiology by Harvey, Champe and Fisher. Second Edition (2007)
2. Mackie and Mc catney, 1994, Medical Microbiology No I and II. Churchill Livingston, 14th edition.
3. Chakraborty P 1995, A Text book of microbiology, New Central Book Agency Pvt Ltd. Calcutta.
Dr.Mohamudha Parveen Rahamathulla
|1 . First Mid term Examination||10 % ()|
|2 . Second Mid term Examination||10 % ()|
|3 . Final Practical Examination||20 % ()|
|4 . Final Theory Examination||50 % ()|
|5 . Participation & Assignment works||10 % ()|
|1 . Knowledge: Outline all fundamental concept of Bacteriology Write , perform and interpret the laboratory tests individually Recognize the methods of bacterial cultivation Tell about anaerobic bacteria Describe the clinical relevance and evidence based decision making||• First midterm exam • Second midterm exam • Attendance and participation • Final Examination|
|2 . Cognitive Skills: Develop to think critically and analytically Compare a clinical problem with the clinical sample Justify the given clinical data Justify the specimens that taken from patients and how to deal with them Explain the causative agent (microorganism) and its susceptibility pattern Write a lab report and interpret with the disease condition/clinical applications||• Written exam • Assignments and Class discussions • Evaluation of lab reports and examinations|
|3 . Interpersonal Skills & Responsibility Use the skills of good listening Choose the responsibility for different aspects of the group work Show the skill of self-learning Show the skills of respecting teachers, colleagues and others Use the skill of team work||• Active class participation reflects the students ability to keep up with the reading schedule • Performance on midterms and final exams are evidence of the student’s ability to recollect and synthesize information|
|4 . Communication, Information Technology, Numerical: Illustrate using PowerPoint and laptop – projector systems Interpret the information needed using internet||Illustrate using PowerPoint and laptop – projector systems Interpret the information needed using internet|
|5 . Psychomotor Examine the microorganism by microscopy, colonial morphology on cultures and confirmatory tests. Illustrate the susceptibility of the microorganisms to antimicrobials Demonstrate basic microbiological instruments||Assignment Practical test to identify microscopic and cultures spots and instruments|
|Week||Description - Reading|
· General Characteristics of bacteria
· Taxonomy and Classification of bacteria
Normal microbial flora of human body:
· General attributes and virulence factors of bacteria causing infections
· Exotoxins, enterotoxins, endotoxins, neurotoxins
· Host Parasite relationships
Harmful Microbial Interactions with Human:
· Entry of pathogens into the host
· Mechanism of bacterial pathogenicity, colonization and growth
· Host factors for infection and innate resistance to infection
Morphology, pathogenicity and laboratory diagnosis of Gram positive organisms- I:
Gram positive organisms-II:
Morphology, pathogenicity and laboratory diagnosis of Mycobacterium spp.
· Mycobacterium Tuberculosis
· Mycobacterium leprae
Treatment of tuberculosis, MDR TB
Morphology, pathogenicity and laboratory diagnosis of Enterobacteriaceae-I:
· Escherichia coli
Morphology, pathogenicity and laboratory diagnosis of Enterobacteriaceae-II:
Emerging bacterial diseases
Study about newly upcoming pathogenic diseases caused by bacteria
Morphology, pathogenicity and laboratory diagnosis of Non- Enterobacteriaceae
Morphology, pathogenicity and laboratory diagnosis of Gram negative bacteria
Sexually transmitted diseases:
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