Faculty Members

Dr.Mohammad Javed Ansari

M.PHARM, PhD (PHARMACEUTICS) Associate Professor Department of Pharmaceutics College of Pharmacy AL-Kharj

Kharj
011-588-0556803670
mj.ansari@psau.edu.sa

Curriculum Vitae
Publications

Research Interests

My area of research includes the Development and formulation of drug delivery systems for poorly soluble drugs with emphasis on solubility and bioavailability enhancement techniques such as cyclodextrin complexation, solid dispersions, micronization, nanonization, energyless microemulsion formation, and self-nano emulsifying drug delivery systems.
I have hands-on experiences and expertise on methodologies and techniques such as physicochemical characterization of drugs and formulations using UV, FTIR, DSC, XRD; Analytical and bioanalytical method developments and validation of techniques such as UV, HPLC; Quantitative assay/evaluations of drugs and formulations in matrix and plasma by HPLC; Physicochemical modifications of drugs; In vitro characterizations of drugs and dosage forms using dissolution, disintegration, diffusion, permeation, particle size estimation; and Pharmacokinetics, bioequivalence/ bioavailability estimations.
I have published more than 60 papers in reputed journals, authored a few book chapters, and have been serving as an editorial board member of reputed journals.

Experience

15-03-2017 - until now - ASSOCIATE PROF. - PRINCE SATTAM BIN ABDULAZIZ UNIVERSITY
25-09-2009 - 15-03-2017 - ASSISTANT PROF - PRINCE SATTAM BIN ABDULAZIZ UNIVERSITY
04-02-2009 - 25-09-2009 - ASSISTANT PROF - COLLEGE OF PHARMACY, KING SAUD UNIVERSITY

Publications

Ansari MJ, Al-Nakhli M, Al-Otaibi T, Manazel O, Anwer MK, Ahmad MM, Alshahrani SM, Alshetaili A, Aldawsari MF, Alalaiwe AS, Alanazi AZ. Formulation and evaluation of self-nanoemulsifying drug delivery system of brigatinib: Improvement of solubility, in vitro release, ex-vivo permeation and anticancer activity. Journal of Drug Delivery Science and Technology. 2021, 61:102204. (Q2, Impact Factor: 3.98).
Mohammad Javed Ansari, Mohammad Ramezanitaghartapeh, Preeti Singla, Mehrdad Aghaei, H. Khandan Fadafan, Sahar Ardalan Khales, Mehdi Shariati, Hanzaleh Balakheyli, Hesamaddin Shirzad-Aski, Syed Sarim Imam, Ameeduzzafar Zafar. Computational and experimental studies of sulfasalazine’s adsorption using hydroxyl functionalized C60 fullerene. Accepted in Journal of Molecular Liquids, 2021, (Q1, Impact Factor: 6.165).
Nabo Sun; Mohammad Javed Ansari, Andrew Ng Kay Lup; Masoud Javan; Alireza Soltani; Seyed Reza Khandoozi; Ali Arian Nia; Samaneh Tavassoli; Mohd Sani Sarjadi; Shaheen M Sarkar; Chia-Hung Su, Hoang Chinh Nguyen. Improved anti-inflammatory and anticancer properties of celecoxib using Zinc oxide and magnesium oxide nanoclusters via molecular docking and density functional theory simulation. Accepted in Arabian Journal of chemistry, 2021, (Q1, Impact Factor: 5.16).
Farhat Fatima , Mohammed F. Aldawsari, Mohammed Muqtader Ahmed , Md. Khalid Anwer, Maimuna Naz , Mohammad Javed Ansari , Abubaker M. Hamad , Ameeduzzafar Zafar , Mohammed Jafar . Green Synthesized Silver Nanoparticles Using Tridax Procumbens for Topical Application: Excision Wound Model and Histopathological Studies. Pharmaceutics, 2021, 13 (11), 1754. (Q1, Impact Factor: 6.07).
Mahak Fatima, Sadia Monawwar, Sradhanjali Mohapatra, Thomson Santosh Alex, Abdulrahman Ahmed, Mohamad Taleuzzaman, Asgar Ali, Mohammad Javed Ansari, Mohd. Aamir Mirza *, Zeenat Iqbal *. In silico drug screening based development of novel formulations for onychomycosis management. Gels, 2021, 7 (04), 221 (Q1, Impact Factor: 4.7).
Kanchan Kohli, Ali Mujtaba, Rozina Malik, Saima Amin , Md Sarfaraz Alam , Abuzer Ali , Md. Abul Barkat, Mohammad Javed Ansari. Development of Natural Polysaccharide–Based Nanoparticles of Berberine to Enhance Oral Bioavailability: Formulation, Optimization, Ex Vivo, and In Vivo Assessment. Polymers, 2021, 13 (21), 3833(Q1, Impact Factor: 4.43).
Sradhanjali Mohapatra, Mohd. Aamir Mirza, Ayah Rebhi Hilles, Foziyah
Zakir, Andreia Castro Gomes, Mohammad Javed Ansari, Zeenat Iqbal *, Syed
Mahmood. Biomedical application, Patent repository, Clinical trial and
Regulatory updates on Hydrogel: An extensive review.Gels, 2021, 7 (4), 207. (Q1, Impact Factor: 4.7).
Ansari MJ, Alshahrani SM. Solubility Determination of Osimertinib Mesylate in Various Solvents by Validated, Rapid, Highly Sensitive, Water Rich Reverse Phase High-Performance Liquid Chromatography Latin American Journal of Pharmacy. 2021, ;40(5):1084-93. (Impact Factor: 0.37).
Singh, A Jain, P Khan, R Anwer, MK, Ansari, MJ, Aqil, M, Mirza, MA, Iqbal, Z. Development and quality evaluation of chitosan-coated cellulose acetate phthalate-poloxamer enamel adhesive device for the treatment of dentin carious lesion. International Journal Of Polymeric Materials And Polymeric Biomaterials, 2021 (Q2, Impact Factor: 2.60).
Mohammed Muqtader Ahmed, Farhat Fatima, Md. Khalid Anwer, Elmutasim Osman Ibnouf, Mohd Abul Kalam, Aws Alshamsan, Mohammed F. Aldawsari, Ahmed Alalaiwe, Mohammad Javed Ansari. Formulation and in vitro evaluation of topical nanosponge-based gel containing butenafine for the treatment of fungal skin infection, Saudi Pharmaceutical Journal, 29,5, 2021,Pages 467-477. (Q1, Impact Factor: 3.11).
Zafar A, Alruwaili NK, Imam SS, Alsaidan OA, Alharbi KS, Yasir M, Elmowafy M, Ansari MJ, Salahuddin M, Alshehri S. Formulation of carteolol chitosomes for ocular delivery: formulation optimization, ex-vivo permeation, and ocular toxicity examination. Cutan Ocul Toxicol. 2021 Aug 3:1-12. doi: 10.1080/15569527.2021.1958225. Epub ahead of print. PMID: 34340615. (Q4, Impact Factor: 1.8).
Oussama Ouerghi, Mohammed H. Geesi, Elmutasim O. Ibnouf, Mohammad Javed Ansari, Pravej Alam, Ammar Elsanousi, Abdellah Kaiba, Yassine Riadi, Sol-gel synthesized rutile TiO2 nanoparticles loaded with cardamom essential oil: Enhanced antibacterial activity, Journal of Drug Delivery Science and Technology, Volume 64, 2021,102581, (Q2, Impact Factor: 2.73).
Ansari MJ, Alshetaili A, Aldayel IA, Alablan FM, Alsulays B, Alshahrani S, Alalaiwe A, Ansari MN, Ur Rehman N, Shakeel F. Formulation, characterization, in vitro and in vivo evaluations of self-nanoemulsifying drug delivery system of luteolin. Journal of Taibah University for Science. 2020 14(1):1386-401. (Q2, Impact Factor: 2.68).
Ansari MJ, Mohammed FA, Iqbal Z, Khuroo A. Determination of Levofloxacin in Human Plasma by HPLC: Method Development, Validation, Stability Evaluation and Application to Pharmacokinetics. Latin American Journal of Pharmacy. 2020, ;39(6):1149-58. (Q4, Impact Factor: 0.37).
Ansari MJ, Ahmed MM, Anwer MK, Aldawsari MF, Al Shahrani SM, Ahmad N. Development and Validation of Simple, Rapid and Sensitive High-Performance Liquid Chromatographic Method for the Determination of Butenafine Hydrochloride. Journal of Pharmaceutical Research International. 2020, 23:116-25. (WoS- ESCI).
Mohammad Javed Ansari, Nehad J. Ahmed, Mohd. Faiyaz Khan, Dina Allam Abdel Maqsoud Hassan. Feedback of Pharmacy Undergraduate Students Regarding the Effectiveness of Theoretical and Practical Courses in the Pharmacy Program. Journal of Pharmaceutical Research International, 2020, 32 (36):12-17. (WoS- ESCI).
Md. Khalid Anwer, Muqtader Mohammad, Nasr Y. Khalil, Faisal Imam, Mohammad Javed Ansari, Mohammed F. Aldawsari, Faiyaz Shakeel, Muzaffar Iqbal, Solubility, thermodynamics and molecular interaction studies of delafloxacin in environmental friendly ionic liquids, Journal of Molecular Liquids, 2020, 305:112854. (Q1, Impact Factor: 6.15).
MM Ahmed, M. K. Anwer, F. Fatima, M.J. Ansari, Saad M.Alshahrani, Development and Characterization of Ethyl cellulose Nanosponges for Sustained release of Brigatinib for the treatment of Non-Small-Cell Lung Cancer" Journal of Polymer Engineering 2020, 40 (10): 823-832 (Q3, Impact Factor: 1.37).
Ansari, M.J. An overview of techniques for multifold enhancement in solubility of poorly soluble drugs. Current Issues in Pharmacy and Medical Sciences, 2019, 32(4): 203-209.(WOS, SCOPUS)
Bader BadiAlsulays ,Shahid Jamil, Mohammad Raish , Mushtaq Ahmad Ansari, Ajaz Ahmad, Ahmed Alalaiwe, Saad Maria Alshahrani, Abdullah Saud Alshetaili, Mohammad Javed Ansari , Sultan Mohammad Alshehri and Nazrulhaq. Influences of Ferulic Acid on Pharmacokinetics of Carbamazepine in Rats: Possible Mechanism of Herb/food-drug Interactions. International Journal of Pharmacology, 15: 978-985. (Q4, Impact Factor: 0.76).
Abdullah S. Alshetaili,* M.J. Ansari,* M. K. Anwer, Majid A. Ganaie, M. Iqbal, SaadM.Alshahrani, Ahmad S. Alalaiwe, Bader S. Alsulays, S. Alshehri and Abdullah Alsultan. Enhanced Oral Bioavailability of Ibrutinib Encapsulated Poly (Lactic-co-Glycolic Acid) Nanoparticles: Pharmacokinetic Evaluation in Rats. Current Pharmaceutical Analysis, 2019, 15 (6): 661-668. (Q3, Impact Factor: 0.89).
Ansari, M.J., & Alshahrani, S. M. Nano-encapsulation and characterization of baricitinib using poly-lactic-glycolic acid co-polymer. Saudi Pharmaceutical Journal 2019, 27(4):491-501.(Q1, Impact Factor: 4.33).
Ahmed Alalaiwe, Paul Carpinone, SaadAlshahrani, Bader Alsulays, Mohammed Ansari, Mohammed Anwer, Sultan Alshehri, Abdullah Alshetaili. Influence of chitosan coating on the oral bioavailability of gold nanoparticles in rats. Saudi Pharmaceutical Journal, 2019, 27 (2):171-175. (Q1, Impact Factor: 4.33).
Alshetaili, A.S., Anwer, M.K., Alshahrani, S.M., Alalaiwe, A., Alsulays, B.B., Ansari, M.J., Imam, F. and Alshehri, S. Characteristics and anticancer properties of Sunitinib malate-loaded poly-lactic-co-glycolic acid nanoparticles against human colon cancer HT-29 cells lines. Tropical Journal of Pharmaceutical Research,2018, 17(7):1263-1269.(Impact Factor: 0.57).
Mohammad Javed Ansari. Factors Affecting Preparation and Properties of Nanoparticles by Nanoprecipitation Method, Indo American Journal of Pharmaceutical Sciences, 2017; 4(12):4854-4858.(Web of Science)
Al-Shahrani, S. and Ansari, M.J. Solubility evaluations of osimertinib mesylate in physiological buffers. Indo American Journal of Pharmaceutical Sciences, 2018, 5(4):2610-2615.(Web of Science)
Mohammad Javed Ansari. Transdermal Drug Delivery Systems: An Emerging Non-Invasive Alternative to Oral and Parenteral Drug Administrations. BAOJ Pharm Sci,2017, 3: 40-44.
PrawezAlam, Mohammad J. Ansari, Khalid Anwer, Mohammad Raish, Yoonus K. T. Kamal, and FaiyazShakeel. Wound healing effects of nanoemulsion containing clove essential oil. Artificial Cells, Nanomedicine, And Biotechnology, 2017, 45(3):591-597. (Impact Factor: 5.6).
M.J. Ansari, Fluconazole loaded nano-emulsion assay by validated rapid and sensitive high performance liquid chromatography. Indo American journal of Pharmaceutical Sciences2017, 4 (04), 976-982. (Web of Science).
Ansari M.J. Preparation and evaluation of di-component and tri-component molecular inclusion complexes of silymarin. Latin American Journal of Pharmacy,2016; 35(3):604-608. (Impact factor: 0.39).
M.J. Ansari, M.M. Ahmed, M.K.Anwer, S. Jamil, A. Alailaiwe, A.S. Alshetaili, R. Shdefat, R. Ali, F. Shakeel. Formulation and characterization of fluconazole loaded olive oil nano-emulsions. Indo American journal of Pharmaceutical Sciences2017, 4 (04), 852-860. (Web of Science).
Ansari MJ, Anwer MK, Jamil S, Al-Shdefat R, Ali BE, Ahmad MM, Ansari MN. Enhanced oral bioavailability of insulin-loaded solid lipid nanoparticles: pharmacokinetic bioavailability of insulin-loaded solid lipid nanoparticles in diabetic rats. Drug Delivery. 2016; 23 (6):1972-1979. (Impact Factor: 6.4).
M.J. Ansari1, M. M. Ahmed1, M.K. Anwer1, S. Jamil1, R. Shdefat, O. Harthi2, M.O. Ibnouf3, Y.S. Nour3, Prawez Alam4, Abdel-Kader MS4.Evaluation of Antifungal Activity of Olive Oil Based Nanoemulsions. Bulletin of Environment, Pharmacology and Life Sciences, 2016; 5(4):1-4.(ISI indexed)
Ansari MJ. Formulation and physicochemical characterization of sodium carboxy methyl cellulose and beta cyclodextrin mediated ternary inclusion complexes of silymarin. Int J Pharm Sci Res 2016; 7(3): 984-90. (Web of science)
Ansari MJ. Oral delivery of insulin for the treatment of diabetes: Classical challenges and current opportunities. Journal of Medical Research, 2015; 15(5):209-220. (Scopus H Index: 8).
Ansari MJ, M.K. Anwer, M. M. Ahmed, S. Jamil, M. Althubaiti. Nano-suspension versus cyclodextrin inclusion of ciprofloxacin for solubility and dissolution enhancement. Journal of Chemical and Pharmaceutical Research, 2015; 7(10): 208-213. (Scopus H Index: 21).
Ansari MJ. Investigations of polyethylene glycol mediated ternary molecular inclusion complexes of silymarin with beta cyclodextrin. Journal of Applied Pharmaceutical Science, 2015;5(9):26-31. (Scopus H Index: 16).
Ansari MJ, M. Althubaiti,MOIbnouf, MK Anwer, MM Ahmed, F Fatima, S Jamil. Enhanced Antibacterial Effects of Ciprofloxacin Enclosed InCyclodextrin and Nano-Suspension Carrier Systems. Bulletin of Environment, Pharmacology and Life Sciences, 2015, 4(11):14-18. (ISI indexed).
Ansari MJ. Solubility and dissolution enhancement of silymarin by ternary inclusion complexation withbetacyclodextrin and hydroxypropyl methyl cellulose. International journal of advanced life sciences, 2015, 8(3):262-269. (ISI indexed).
Ansari MJ. Role of protease inhibitors in Insulin therapy of Diabetes: are these beneficial? Bulletin of Environment, Pharmacology and Life Sciences, 2015; 4(11): 1-8. (ISI indexed).
Ansari MJ and Ahmad MM. Physicochemical characterizations, dissolution behavior and release kinetics of curcumin and β-cyclodextrin molecular inclusion complexes. International Journal of Pharma and Biosciences, 2015; 6(1):85-95. (Scopus H index 16).
Anwer MK, Jamil S, Ansari MJ, Al-Shdefat R, Ali BE, Ganaie MA, Abdel-Kader MS, Shakeel F. Water soluble binary and ternary complexes of diosmin with β-cyclodextrin: Spectroscopic characterization, release studies and anti-oxidant activity. Journal of Molecular Liquids. 2014; 199: 35-41. (Impact Factor: 3.65).
Ansari MJ, Jamil S, Anwer MK, Al-shdefat R, Ali BE. Development and validation of simple and rapid high performance liquid chromatographic method for routine analysis of human insulin in formulations. African Journal of Pharmacy and Pharmacology, 2014; 8(40): 1018-1024. (Scopus H Index: 17).
Ansari MJ, Kohli K, Ali J, Anwer MK, Jamil S, Ahmad MM. Physicochemical characterizations and dissolution behavior of curcumin and α-cyclodextrin molecular inclusion complexes. Der Pharmacia Letter, 2014; 6(6):1-7. (Scopus H index 13).
Ansari MJ, Ahmed MM, Fatima F, Anwer MK, Jamil S, Al-shdefat R, Ali BE, Al-Awmi F and Abdel-Kader MS. solubility and stability enhancement of curcumin through cyclodextrin complexation. International Journal of Biology, Pharmacy and Allied Sciences. 2014; 3(11): 2668-2675. (ISI indexed).
Ansari MJ, Ahmed MM, Fatima F, Anwer MK, Jamil S, Al-shdefat R, Ali BE, Al-Awmi F and Abdel-Kader MS. Influence of hydrophilic polymers on complexation and solublizing efficiencies of beta cyclodextrin over silymarin. International Journal of Biology, Pharmacy and Allied Sciences. 2014; 3(10): 237-242. (ISI indexed).
FI Al-Jenoobi, AA Al-Thukair, FA Abbas, MJ Ansari, KM Alkharfy, AM Al-Mohizea, SA Al-Suwayeha, S Jamil. Effect of black seed on Dextromethorphan O-and N- Demethylation in human liver microsomes and healthy human subjects. Drug Metabolism Letters, 2010; 4(1):51-55. (Scopus H index 20).
Ansari MJ, Kohli K, Dixit N. Microemulsions as potential drug delivery systems: a review. PDA Journal Pharmaceutical Science Technology, 2008; 62(1):66-79. (Scopus H index 28).
MJ Ansari, K Kohli, J Ali, MT Anwer. Enhanced anti-inflammatory activity of curcumin, a naturally occurring pigment in turmeric. Oriental Pharmacy and Experimental Medicine. 2007; 2 (1):34-42. (Scopus H index 5).
K Kohli, J Ali, MJ Ansari and Z Raheman. Curcumin: a natural anti-inflammatory agent. Indian Journal of Pharmacology, 2005; 37: 141-147. (Impact Factor 0.69).
MJ Ansari, S Ahmad, K Kohli, J Ali, and R. K. Khar. Stability-indicating HPTLC determination of curcumin in bulk drug and pharmaceutical formulations. Journal of Pharmaceutical and Bio-medical Analysis. 2005; 39: 132-138. (Impact Factor 3.255).

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Dr.Mohammad Javed Ansari

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Faculty Members

Dr.Mohammad Javed Ansari

Research Interests

Experience

Publications

Administration of Public Relations and Media