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Breadcrumb

  1. الرئيسية /
  2. أعضاء هيئة التدريس /

د.محمد حامد سعيد القرنى

PhD pharmaceutical sciences استاذ مشارك قسم العقاقير كلية الصيدلة بالخرج
  • الخرج
  • 011-588-6011
  • m.alqarni@psau.edu.sa
  • السيرة الذاتية
  • الأبحاث العلمية

المؤهلات العلمية

  • PhD. School of Pharmacy - University of Pittsburgh

  • B.S. School of Pharmacy- King Saud University, Saudi Arabia

الاهتمامات البحثية

  • Chromatography: TLC, Open column chromatography, Gel Chromatography (Sephadex and Polyamide support), Preparative HPLC.
  • Protein analysis: Cell culturing (Bacterial and Viral culturing), computer simulation and modeling, fast protein liquid chromatography (FPLC) and protein analysis (circular dichroism spectroscopy).

مهام ومسؤوليات

  • رئيس قسم العقاقير - كلية الصيدلة

الأبحاث العلمية

  • .A. Dound, S. Chaudhary, S.S. Chaudhary, S. Rawat, M.H. Alqarni, M.M. Ahmad, M.H. Geesi, P. Alam, Mechanistic understanding of PtyroneTM: A plant based natural anti diabetic product, J King Saud Univ Sci, 33 (2021).
  • 2. A.K. Garg, B. Maddiboyina, M.H.S. Alqarni, A. Alam, H.M. Aldawsari, P. Rawat, S. Singh, P. Kesharwani, Solubility enhancement, formulation development and antifungal activity of luliconazole niosomal gel-based system, J Biomat Sci-Polym E, 32 (2021) 1009-1023.
  • 3. M. Platis, D. Vlachakis, A.I. Foudah, M.M. Muharram, M.H. Alqarni, A.C. Papageorgiou, N.E. Labrou, The Interaction of Schistosoma japonicum Glutathione Transferase with Cibacron Blue 3GA and its Fragments, Med Chem, 17 (2021) 332-343.
  • 4. M.H. Alqarni, A.I. Foudah, M.M. Muharram, H. Budurian, N.E. Labrou, Probing the Role of the Conserved Arg174 in Formate Dehydrogenase by Chemical Modification and Site-Directed Mutagenesis, Molecules, 26 (2021).
  • 5. M.H. Alqarni, A.I. Foudah, M.M. Muharram, N.E. Labrou, The Interaction of the Flavonoid Fisetin with Human Glutathione Transferase A1-1, Metabolites, 11 (2021).
  • 6. M.H. Alqarni, A.I. Foudah, M.M. Muharram, N.E. Labrou, The Interaction of Human Glutathione Transferase GSTA1-1 with Reactive Dyes, Molecules, 26 (2021).
  • 7. P. Alam, M.M. Salem-Bekhit, F.A. Al-Joufi, M.H. Alqarni, F. Shakeel, Quantitative analysis of cabozantinib in pharmaceutical dosage forms using green RP-HPTLC and green NP-HPTLC methods: A comparative evaluation, Sustain Chem Pharm, 21 (2021).
  • 8. P. Alam, F. Shakeel, M.H. Alqarni, A.I. Foudah, M. Faiyazuddin, S. Alshehri, Rapid, Sensitive, and Sustainable Reversed-Phase HPTLC Method in Comparison to the Normal-Phase HPTLC for the Determination of Pterostilbene in Capsule Dosage Form, Processes, 9 (2021).
  • 9. M.H. Alqarni, P. Alam, A.I. Foudah, M.M. Muharram, F. Shakeel, Combining Normal/Reversed-Phase HPTLC with Univariate Calibration for the Piperine Quantification with Traditional and Ultrasound-Assisted Extracts of Various Food Spices of Piper nigrum L. under Green Analytical Chemistry Viewpoint, Molecules, 26 (2021).
  • 10. A.I. Foudah, F. Shakeel, M.H. Alqarni, S.A. Ross, M.A. Salkini, P. Alam, Green NP-HPTLC and green RP-HPTLC methods for the determination of thymoquinone: A contrast of validation parameters and greenness assessment, Phytochem Analysis, (2021).
  • 11. A.I. Foudah, F. Shakeel, M.H. Alqarni, S.A. Ross, M.A. Salkini, P. Alam, Simultaneous Estimation of Cinnamaldehyde and Eugenol in Essential Oils and Traditional and Ultrasound-Assisted Extracts of Different Species of Cinnamon Using a Sustainable/Green HPTLC Technique, Molecules, 26 (2021).
  • 12. M. Ghazwani, M.Y. Begum, P. Alam, M.H. Alqarni, H.S. Yusufoglu, F. Shakeel, Solubility Determination, Hansen Solubility Parameters and Thermodynamic Evaluation of Thymoquinone in (Isopropanol plus Water) Compositions, Molecules, 26 (2021).
  • 13. M. Ghazwani, P. Alam, M.H. Alqarni, H.S. Yusufoglu, F. Shakeel, Solubilization of Trans-Resveratrol in Some Mono-Solvents and Various Propylene Glycol plus Water Mixtures, Molecules, 26 (2021).
  • 14. P. Alam, M.M. Salem-Bekhit, M. Iqbal, M.K. Anwer, M.H. Alqarni, F. Shakeel, Stability-indicating reversed-phase/normal-phase high-performance thin-layer chromatography technique for the determination of arbidol: Green analytical chemistry viewpoint, J Chin Chem Soc-Taip, 68 (2021) 1709-1721.
  • 15. M. Khalid, M.H. Alqarni, A. Shoaib, M. Arif, A.I. Foudah, O. Afzal, A. Ali, A. Ali, S.S. Alqahtani, A.S.A. Altamimi, Anti-Arthritic and Anti-Inflammatory Potential of Spondias mangifera Extract Fractions: An In Silico, In Vitro and In Vivo Approach, Plants-Basel, 10 (2021).
  • 16. A.I. Foudah, F. Shakeel, P. Alam, M.H. Alqarni, M.S. Abdel-Kader, S. Alshehri, A Sustainable Reversed-Phase HPTLC Method for the Quantitative Estimation of Hesperidin in Traditional and Ultrasound-Assisted Extracts of Different Varieties of Citrus Fruit Peels and Commercial Tablets, Agronomy-Basel, 11 (2021).
  • 17. A.I. Foudah, M.H. Alqarni, A. Alam, M.A. Salkini, E.O.I. Ahmed, H.S. Yusufoglu, Evaluation of the composition and in vitro antimicrobial, antioxidant, and anti-inflammatory activities of Cilantro (Coriandrum sativum L. leaves) cultivated in Saudi Arabia (Al-Kharj), Saudi J Biol Sci, 28 (2021) 3461-3468.
  • 18. P. Alam, F. Shakeel, M.H. Alqarni, A.I. Foudah, A rapid and highly sensitive stability-indicating high-performance thin-layer chromatography technique for the determination of tedizolid phosphate with a classical univariate calibration, Jpc-J Planar Chromat, 34 (2021) 271-278.
  • 19. A.I. Foudah, F. Shakeel, M.H. Alqarni, P. Alam, A rapid and sensitive stability-indicating green RP-HPTLC method for the quantitation of flibanserin compared to green NP-HPTLC method: Validation studies and greenness assessment, Microchem J, 164 (2021).
  • 20. P. Alam, M.H. Alqarni, F. Shakeel, Phytochemical Analysis, Standardization and Antidiabetic Effects of Tinospora cordifolia Stems, Lat Am J Pharm, 40 (2021) 1931-1938.
  • 21. M.H. Alqarni, P. Alam, F. Shakeel, A.I. Foudah, S. Alshehri, Highly Sensitive and Ecologically Sustainable Reversed-Phase HPTLC Method for the Determination of Hydroquinone in Commercial Whitening Creams, Processes, 9 (2021).
  • 22. M.H. Alqarni, N. Haq, P. Alam, M.S. Abdel-Kader, A.I. Foudah, F. Shakeel, Solubility data, Hansen solubility parameters and thermodynamic behavior of pterostilbene in some pure solvents and different (PEG-400+water) cosolvent compositions, J Mol Liq, 331 (2021).
  • 23. M.S. Abdel-Kader, M.H. Alqarni, A.I. Foudah, New Flavonoids from Saudi collection of Tephrosia purpurea L. (Pers.), Rec Nat Prod, 15 (2021) 293-300.
  • 24. P. Alam, M.T. Alanazi, H.H. Zaatout, M.H. Alqarni, M.S. Abdel-Kader, Densitometric high-performance thin-layer chromatography methods for the quantification of oleuropein in Olea europaea leaves and pharmaceutical preparation utilizing normal- and reversed-phase silica gel plates (vol 33, pg 609, 2020), Jpc-J Planar Chromat, (2021).
  • 25. M.H. Alqarni, A.I. Foudah, A. Alam, M.A. Salkini, P. Alam, H.S. Yusufoglu, Novel HPTLC-densitometric method for concurrent quantification of linalool and thymol in essential oils, Arab J Chem, 14 (2021).
  • 26. M. Khalid, M.H. Alqarni, A.I. Foudah, P. Alam, A high-performance thin-layer chromatography method for the simultaneous determination of quercetin and gallic acid in Eclipta alba and Guiera senegalensis, Jpc-J Planar Chromat, 34 (2021) 71-77.
  • 27. M.M. Muharram, A.T. Abulhamd, M.F. Aldawsari, M.H. Alqarni, N.E. Labrou, Development of Staphylococcus Enzybiotics: The Ph28 Gene of Staphylococcus epidermidis Phage PH15 Is a Two-Domain Endolysin, Antibiotics-Basel, 9 (2020).
  • 28. A.I. Foudah, M.H. Alqarni, G.A. Soliman, R.F. Abdel-Rahman, O. Alankus-Caliskan, M.A. Ganaie, H. Yusufoglu, The Potential Hepatoprotective and Antioxidant Activities of Astragalus davisii against Paracetamol Induced Liver Damage in Rats, J Pharm Res Int, 32 (2020) 102-114.
  • 29. P. Alam, E. Ezzeldin, M. Iqbal, G.A.E. Mostafa, M.K. Anwer, M.H. Alqarni, A.I. Foudah, F. Shakeel, Determination of Delafloxacin in Pharmaceutical Formulations Using a Green RP-HPTLC and NP-HPTLC Methods: A Comparative Study, Antibiotics-Basel, 9 (2020).
  • 30. M.H. Alqarni, G.A. Soliman, M.A.A. Salkini, P. Alam, H.S. Yusufoglu, S. Baykan, B. Ozturk, M.S. Abdel-Kader, The Potential Aphrodisiac Effect of Ferula drudeana Korovin Extracts and Isolated Sesquiterpene Coumarins in Male Rats, Pharmacogn Mag, 16 (2020) S404-S409.
  • 31. M.H. Alqarni, M. Ghazwani, M.K. Anwer, F. Shakeel, P. Alam, Determination of Sunitinib Malate in Nanoparticles Formulation Using HPTLC-Densitometry Technique, Lat Am J Pharm, 39 (2020) 2279-2284.
  • 32. P. Alam, M.H. Alqarni, P. Alam, A.I. Foudah, M. Ghazwani, A HPTLC Method for Determination of Anethole in Essential Oil, Methanolic Extract of Foeniculum vulgare and Commercial Herbal Products, J Pharm Res Int, 32 (2020) 68-75.
  • 33. M. Khalid, M.H. Alqarni, A.I. Foudah, J. Akhtar, Badruddeen, A. Shoaib, P. Alam, Evaluation of Free Radical Scavenging Potential of Different Bioactive Fractions Present in Boerhavia diffusa Linn. Root Extract: An in-vitro Approach, J Pharm Res Int, 32 (2020) 99-107.
  • 34. P. Alam, N. Haq, M.H. Alqarni, F. Shakeel, Quantitative Analysis of Emtricitabine in Dosage Forms Using Green RP-HPTLC and Routine NP-HPTLC Methods-A Contrast of Validation Parameters, ACS Omega, 5 (2020) 33470-33477.
  • 35. A.I. Foudah, F. Shakeel, M.H. Alqarni, H.S. Yusufoglu, M.A. Salkini, P. Alam, Determination of Trans-Anethole in Essential Oil, Methanolic Extract and Commercial Formulations of Foeniculum vulgare Mill Using a Green RP-HPTLC-Densitometry Method, Separations, 7 (2020).
  • 36. M. Khalid, A. Shoaib, J. Akhtar, M.H. Alqarni, Badruddeen, H.H. Siddiqui, A.I. Foudah, Anti obesity prospective of Dalbergia latifolia (Roxb.) hydroalcoholic bark extract in high fat diet induced obese rats, 3 Biotech, 10 (2020) 493.
  • 37. P. Alam, M. Iqbal, E. Ezzeldin, N.Y. Khalil, A.I. Foudah, M.H. Alqarni, F. Shakeel, Simple and Accurate HPTLC-Densitometric Method for Quantification of Delafloxacin (A Novel Fluoroquinolone Antibiotic) in Plasma Samples: Application to Pharmacokinetic Study in Rats, Antibiotics (Basel), 9 (2020).
  • 38. P. Alam, M. Iqbal, A.I. Foudah, M.H. Alqarni, F. Shakeel, Quantitative determination of canagliflozin in human plasma samples using a validated HPTLC method and its application to a pharmacokinetic study in rats, Biomed Chromatogr, 34 (2020) e4929.
  • 39. P. Alam, P. Alam, M.A. Sharaf-Eldin, M.H. Alqarni, Simultaneous identification of rutin, chlorogenic acid and gallic acid in Moringa oleifera by densitometric high-performance thin-layer chromatography method, Jpc-J Planar Chromat, 33 (2020) 27-32.
  • 40. A.I. Foudah, P. Alam, F. Shakeel, S.I. Alqasoumi, M.H. Alqarni, H.S. Yusufoglu, Eco-Friendly RP-HPTLC Method for Determination of Valerenic Acid in Methanolic Extract of Valeriana officinalis and Commercial Herbal Products, Lat Am J Pharm, 39 (2020) 420-424.
  • 41. P. Alam, E. Ezzeldin, M. Iqbal, M.K. Anwer, G.A.E. Mostafa, M.H. Alqarni, A.I. Foudah, F. Shakeel, Ecofriendly densitometric RP-HPTLC method for determination of rivaroxaban in nanoparticle formulations using green solvents, Rsc Adv, 10 (2020) 2133-2140.
  • 42. A.I. Foudah, P. Alam, Y.T. Kamal, S.I. Alqasoumi, M.H. Alqarni, S.A. Ross, H.S. Yusufoglu, Development and validation of a high-performance thin-layer chromatographic method for the quantitative analysis of vitexin in Passiflora foetida herbal formulations, Saudi Pharm J, 27 (2019) 1157-1163.
  • 43. P. Alam, M.S. Abdel-Kader, M.H. Alqarni, H.H. Zaatout, S.R. Ahamad, F. Shakeel, Chemical composition of fennel seed extract and determination of fenchone in commercial formulations by GC-MS method, J Food Sci Tech Mys, 56 (2019) 2395-2403.
  • 44. P. Alam, Y.T. Kamal, S.I. Alqasoumi, A.I. Foudah, M.H. Alqarni, H.S. Yusufoglu, HPTLC method for simultaneous determination of ascorbic acid and gallic acid biomarker from freeze dry pomegranate juice and herbal formulation, Saudi Pharm J, 27 (2019) 975-980.
  • 45. M.S. Abdel-Kader, A.M. Hamad, M.T. Alanazi, A.H. Alanazi, R. Ali, A.I. Foudah, M.H. Alqarni, Characterization and hepatoprotective evaluation of sesquiterpenes and diterpenes from the aerial parts of Juniperus sabina L., Saudi Pharm J, 27 (2019) 920-929.
  • 46. M.S. Abdel-Kader, G.A. Soliman, M.H. Alqarni, A.M. Hamad, A.I. Foudah, S.I. Alqasoumi, Chemical composition and protective effect of Juniperus sabina L. essential oil against CCl4 induced hepatotoxicity, Saudi Pharm J, 27 (2019) 945-951.
  • 47. A.I. Foudah, P. Alam, M.H. Alqarni, M.A.A. Salkini, M.S. Abdel-Kader, Development of a Reversed-Phase High-Performance Thin-Layer Chromatography Method for the Simultaneous Determination of Trigonelline and Diosgenin Biomarkers in Trigonella foenum-graecum L. Seeds Grown in Variable Environment, Jpc-J Planar Chromat, 32 (2019) 379-384.
  • 48. M.H. Alqarni, P. Alam, A.M. Al Kharji, M.A.A. Salkini, M.S. Abdel-Kader, Effect of Environmental Conditions on the Biomarker Trigonelline in Trigonella foenum-graecum L. seeds Using Validated HPTLC Method, Curr Pharm Anal, 16 (2020) 698-704.
  • 49. M.H. Alqarni, A.I. Foudah, A. Alam, M.A. Salkini, O.A.O. Elmakki, H.S. Yusufoglu, Contribution to the Quality Control and in-Vitro Antioxidant Activity of Leaves of Petroselinum Crispum and Coriandrum Sativum Cultivated in Saudi Arabia, Int J Pharm Sci Res, 10 (2019) 4158-4166.
  • 50. F. Shakeel, P. Alam, M.K. Anwer, S. Alanazi, I.A. Alsarra, M.H. Alqarni, Wound healing evaluation of self-nanoemulsifying drug delivery system containing Piper cubeba essential oil, 3 Biotech, 9 (2019).
  • 51. M.H. Alqarni, M.M. Muharram, S.M. Alshahrani, N.E. Labrou, Copper-induced oxidative cleavage of glutathione transferase F1-1 from Zea mays, Int J Biol Macromol, 128 (2019) 493-498.
  • 52. A.I. Foudah, M. H Alqarni, A. Alam, M.A. Salkini, E.O. Ahmed, H. Yusufoglu, Evaluation of in Vitro Antioxidant and Antimicrobial Activities of Methanol Extract of Standardized Lactuca Sativa L. Leaves, Indo Am J Pharm Sci, 6 (2019) 4277-4290.
  • 53. M.S. Abdel-Kader, K.S. Al Shahrani, M.H. Alqarni, M.A. Salkini, E.H. Khamis, H.A. Ghabbour, S.I. Alqasoumi, Effect of hydroxylated solvents on the active constituents of Salvadora persica root "Siwak", Saudi Pharm J, 27 (2019) 220-224.
  • 54. M.H. Alqarni, P. Alam, M.A. Salkini, M.S. Abdel-Kader, Roasting Effect on the Caffeine Contents and Antioxidant Potential of Different Coffee Grades Available in the Saudi Market, Indo Am J Pharm Sci, 5 (2018) 16738-16745.
  • 55. M.H. Alqarni, M.M. Muharram, N.E. Labrou, Ligand-induced glutathione transferase degradation as a therapeutic modality: Investigation of a new metal-mediated affinity cleavage strategy for human GSTP1-1, Int J Biol Macromol, 116 (2018) 84-90.
  • 56. Y.T. Kamal, P. Alam, S.I. Alqasoumi, A.I. Foudah, M.H. Alqarni, H.S. Yusufoglu, Investigation of antioxidant compounds in commercial pomegranate molasses products using matrix-solid phase dispersion extraction coupled with HPLC, Saudi Pharm J, 26 (2018) 839-844.
  • 57. P. Alam, F. Shakeel, M.K. Anwer, A.I. Foudah, M.H. Alqarni, Wound Healing Study of Eucalyptus Essential Oil Containing Nanoemulsion in Rat Model, J Oleo Sci, 67 (2018) 957-968.
  • 58. M.S. Abdel-Kader, E.H. Khamis, A.I. Foudah, M.H. Alqarni, GC quantitative analysis of benzyl isothiocyanate in Salvadora persica roots extract and dental care herbal products, Saudi Pharm J, 26 (2018) 462-466.
  • 59. H.S. Yusufoglu, G.A. Soliman, A.I. Foudah, M.S. Abdel-Kader, M.H. Alqarni, A. Alam, M.A. Salkini, Standardization and Antioxidant Studies of Arnebia hispidissima, Int J Pharmacol, 14 (2018) 428-436.
  • 60. P. Alam, Y.T. Kamal, M.H. Alqarni, H.H. Zaatout, M.S. Abdel-Kader, Reversed-Phase High-Performance Thin-Layer Chromatographic Method for the Simultaneous Determination of Glycyrrhizin and Glabridin Biomarkers in Glycyrrhiza glabra Roots, Rhizomes and Herbal Formulations, Jpc-J Planar Chromat, 31 (2018) 135-142.
  • 61. H.S. Yusufoglu, M.N. Ansari, G.A. Soliman, A.I. Foudah, M.H. Alqarni, A. Alam, M.A. Salkini, Cardioprotective and Nephroprotective Actions of Methanolic Extract of Pulicaria Somalensis Herbs against Carbon Tetrachloride Induced Toxicity in Rats, Indo Am J Pharm Sci, 5 (2018) 2811-2823.
  • 62. M.S. Abdel-Kader, P. Alam, M.H. Alqarni, M.A. Salkini, High-Performance Thin-Layer Chromatographic Method for the Estimation of Benzyl Isothiocyanate in Salvadora persica Root Extract and Dental Care Herbal Products, Jpc-J Planar Chromat, 30 (2017) 211-215.
  • 63. M.S. Abdel-Kader, M.M. Muharram, A.I. Foudah, M.H. Alqarni, M.A. Salkini, Antimicrobial Isothiocyanate Derivatives from Salvadora Persica Root "Siwak" Extract, Indo Am J Pharm Sci, 4 (2017) 1224-1228.
  • 64. M.S. Abdel-Kader, Y.T. Kamal, P. Alam, M.H. Alqarni, A.I. Foudah, Quantitative Analysis of Benzyl Isothiocyanate in Salvadora persica Extract and Dental Care Herbal Formulations Using Reversed Phase C18 High-Performance Liquid Chromatography Method, Pharmacogn Mag, 13 (2017) S412-S416.
  • 65. J.P. Hu, Z.W. Feng, S.F. Ma, Y. Zhang, Q. Tong, M.H. Alqarni, X.J. Gou, X.Q. Xie, Difference and Influence of Inactive and Active States of Cannabinoid Receptor Subtype CB2: From Conformation to Drug Discovery, J Chem Inf Model, 56 (2016) 1152-1163.
  • 66. Z.W. Feng, M.H. Alqarni, P. Yang, Q. Tong, A. Chowdhury, L.R. Wang, X.Q. Xie, Modeling, Molecular Dynamics Simulation, and Mutation Validation for Structure of Cannabinoid Receptor 2 Based on Known Crystal Structures of GPCRs, J Chem Inf Model, 54 (2014) 2483-2499.
  • 67. M.H. Alqarni, K.Z. Myint, Q. Tong, P. Yang, P. Bartlow, L.R. Wang, R.T. Feng, X.Q. Xie, Examining the critical roles of human CB2 receptor residues Valine 3.32 (113) and Leucine 5.41 (192) in ligand recognition and downstream signaling activities, Biochem Bioph Res Co, 452 (2014) 334-339.
  • 68. P. Yang, K.Z. Myint, Q. Tong, R.T. Peng, H.P. Cao, A.A. Almehizia, M.H. Alqarni, L.R. Wang, P. Bartlow, Y.D. Gao, J. Gertsch, J. Teramachi, N. Kurihara, G.D. Roodman, T. Cheng, X.Q. Xie, Lead Discovery, Chemistry Optimization, and Biological Evaluation Studies of Novel Biamide Derivatives as CB2 Receptor Inverse Agonists and Osteoclast Inhibitors, J Med Chem, 55 (2012) 9973-9987.

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