أعضاء هيئة التدريس | مواقع أعضاء هيئة التدريس

د.غلام مصطفى . حسن

Ph.D. Biochemistry أستاذ مساعد قسم العلوم الطبية الأساسية كلية الطب بالخرج

الخرج
011-588-0507455811
g.hasan@psau.edu.sa

السيرة الذاتية
الأبحاث العلمية

المؤهلات العلمية

دكتوراه. الكيمياء الحيوية

الاهتمامات البحثية

الكيمياء الحيوية (توصيل الأدوية)

الخبرات

1/10/2013 - حتى الآن - استاذ مساعد - جامعة الأمير سطام بن عبد العزيز

مهام ومسؤوليات

تدريس طب الكيمياء الحيوية كلية الطب جامعة الأمير سطام بن عبد العزيز ، الخرج ، المملكة العربية السعودية منسق مختبرات كلية الطب الطب جامعة الأمير سطام بن عبد العزيز ، الخرج ، المملكة العربية السعودية منسق وحدة طب الجهاز البولي بكلية الطب جامعة الأمير سطام بن عبد العزيز ، الخرج ، المملكة العربية السعودية

الأبحاث العلمية

1. Hasan GM, Garg N, Dogra E, Surolia R, Ghosh PC. Inhibition of the Growth of Plasmodium falciparum in Culture by Stearylamine-Phosphatidylcholine Liposomes. J Parasitol Res. 2011; 2011: 1-9
2. Hasan GM, Sheikh IA, Karim S, Haque A, Kamal MA, Chaudhary AG, Azhar E, Mirza. Effect of electromagnetic radiations on neurodegenerative diseases- technological revolution as a curse in disguise. CNS Neurol Disord Drug Targets. 2014; 13(8):1406-12.
3. Hasan GM, Gorea RK, Rahman S. Diagnostic efficacy of cardiac troponins in post-mortem examination of cases with acute myocardial infarction. International Journal of Ethics, Trauma & Victimology 2015;1(1): 21-28
4. Rajendran V, Hasan GM, Neeraj Kumar, Suparna Dutt, Neha Garg, Pooja Tiwari and Prahlad C. Ghosh. Therapeutic efficacy of chloroquine in long circulating liposome formulations against chloroquine- esistant Plasmodium berghei infection in mice. European Journal of Biomedical and Pharmaceutical sciences. 2016; 3(11): 258-264
5. Vijay Kumar, Hasan GM, and Md. Imtaiyaz Hassan Unraveling the Role of RNA Mediated Toxicity of C9orf72 Repeats in C9-FTD/ALS. FRONTIERS IN NEUROSCIENCE. 2017; 11 (711): 1-10
6. Ahmad Abu Turab Naqvi, Hasan GM and Md. Imtaiyaz Hassan. Investigating the role of transcription factors of pancreas development in pancreatic cancer. Pancreatology. 2018; 18 (2018): 184-190
7. Khan MS, Gorea RK, Qamar S, Hasan GM, Gorea A. Some ethical perspective in the discipline of Microbiology. Int J Eth Trauma Victimology 2015; 1(2):45-50.
8. Rajendran V, Rohra S, Raza M, Hasan GM, Dutt S, Ghosh PC. Stearylamine Liposomal Delivery of Monensin in combination with free Artemisinin eliminates blood stages of P. falciparum in culture and P. berghei infection in Murine Malaria. Antimicrob Agents Chemother. March, 2016; 60 (3): 1304-1318
9. Swaminarayan Y, Gorea RK, Gorea A, Khan MS, Hasan GM. Lesch-Nyhan Syndrome: In a Yemini female child. Int J Eth Trauma Victimology 2016; 2(1):54-57
10. Parvez Khan, Manzoor S, Queen A, Naz F, Hasan GM, Suaib Luqman,Asimul Islam, Faizan Ahmad and Md. Imtaiyaz Hassan. Elucidation of Dietary Polyphenolics as Compelling Inhibitorof Microtubule Affinity Regulating Kinase 4: In silico and In vitro Studies. Scientific Reports. 2017; 7 (9470): 1-15
11. Mohd. Shahbaaz, Mohd. Amir, Safikur Rahman, Hasan GM, Ravins Dohare, Krishna Bisetty, Jihoe Kim, Faizan Ahmad, Md. Imtaiyaz Hassan. Structural insights into Rab21 GTPase Activation mechanism by molecular dynamics simulations. Molecular Simulation. 2018; 44 (3): 179-189
12. Farha Naz, Faez Iqbal Khan, Taj Mohammad, Parvez Khan, Saaliqa Manzoor, Hasan GM, Kevin A. Lobb, Suaib Luqman, Asimul Islam, Faizan Ahmad, Md. Imtaiyaz Hassan. Investigation of molecular mechanism of recognition between citral and MARK4: A newer therapeutic approach to attenuate cancer cell progression. Int J Biol Macromol. 2018; 107 (2018): 2580-2589
13. Sunayana Begum Syed, Faez Iqbal Khan, Sabab Hasan Khan, Saurabha Srivastava , Hasan GM, Kevin A. Lobb, Asimul Islam, Faizan Ahmad, Md. Imtaiyaz Hassan. Mechanistic insights into the urea-induced denaturation of kinase domain of human integrin linked kinase. Int J Biol Macromol. 2018; 111 (2018): 208-218
14. Shagufta Khan, Faez Iqbal Khan, Taj Mohammad, Parvez Khan, Hasan GM, Kevin A. Lobb, Asimul Islam, Faizan Ahmad, Md. Imtaiyaz Hassan. Exploring molecular insights into the interaction mechanism of cholesterol derivatives with the Mce4A: A combined spectroscopic and molecular dynamic simulation studies. Int J Biol Macromol. 2018; 111 (2018): 548-560
15. Syed SB, Khan FI, Khan SH, Srivastava S, Hasan GM, Lobb KA, Islam A, Hassan MI, Ahmad F1.Unravelling the unfolding mechanism of human integrin linked kinase by GdmCl-induced denaturation. Int J Biol Macromol. 2018 Jun 6; 117:1252-1263.
16. Khan NS, Khan P, Ansari MF, Srivastava S, Hasan GM, Husain M, Hassan MI. Thienopyrimidine-Chalcones Hybrid Molecules Inhibits Fas-activated Serine/Threonine Kinase: An Approach to Ameliorates Antiproliferation in Human Breast Cancer Cells. Mol Pharm. 2018 Jul 24.
17. RK Gorea, Bindu Aggarwal, Hasan GM, M Sarosh Khan, Sameer al Ghamdi, Arshdeep Gorea, Abhinav Gorea. Attitude and behavior of medical and dental students towards driving in Punjab province of India. Forensic Res Criminol Int J. 2018; 6(3):141‒145.
18. Gulzar M, Syed SB, Khan FI, Khan P, Ali S, Hasan GM, Taneja P, Hassan MI. Elucidation of interaction mechanism of ellagic acid to the integrin linked kinase. Int J Biol Macromol. 2019 Feb 1; 122:1297-1304.
19. Naqvi AAT, Mohammad T, Hasan GM, Hassan MI. Advancements in docking and Molecular dynamics simulations towards ligand-receptor interactions and structure- function relationships. Curr Top Med Chem. 2018; 18(20):1755-1768.
20. Maria Voura, Parvez Khan, Savvas Thysiadis, Sotiris Katsamakas, Aarfa Queen, Gulam Mustafa Hasan, Sher Ali, Vasiliki Sarli, Md Imtaiyaz Hassan. Probing the Inhibition of Microtubule Affinity Regulating Kinase 4 by N-Substituted Acridones. Scientific Reports. 2019 Feb 8;9(1):1676.
21. Mohd Amir, Taj Mohammad, Kartikay Prasad, Gulam Mustafa Hasan, Vijay Kumar, Ravins Dohare, Asimul Islam, Faizan Ahmad, Md Imtaiyaz Hassan. Virtual High- Throughput Screening of Natural Compounds In-Search of Potential Inhibitors for Protection of Telomeres 1 (POT1). J Biomol Struct Dyn. 2019 Oct 31;1-10
22. Mohd Amir, Shahzaib Ahamad, Taj Mohammad, Deeba Shamim Jairajpuri, Gulam Mustafa Hasan, Ravins Dohare, Asimul Islam, Faizan Ahmad, Md Imtaiyaz Hassan. Investigation of Conformational Dynamics of Tyr89Cys Mutation in Protection of Telomeres 1 Gene Associated with Familial Melanoma. J Biomol Struct Dyn. 2019 Dec 27;1-10.
23. Ahmad Abu Turab Naqvi, Gulam Mustafa Hasan, Md Imtaiyaz Hassan. Targeting Tau Hyperphosphorylation via Kinase Inhibition: Strategy to Address Alzheimer's Disease. Curr Top Med Chem. 2020; 20(12):1059-1073.
24. Ahmad Abu Turab Naqvi, Deeba Shamim Jairajpuri, Afzal Hussain, Gulam Mustafa Hasan, Mohamed F Alajmi, Md Imtaiyaz Hassan. Impact of Glioblastoma Multiforme Associated Mutations on the Structure and Function of MAP/microtubule Affinity Regulating Kinase 4. J Biomol Struct Dyn. 2020 Mar 17;1-14.
25. Saleha Anwar, Taj Mohammad, Anas Shamsi, Aarfa Queen, Shahnaz Parveen, Suaib Luqman, Gulam Mustafa Hasan, Khalid A Alamry, Naved Azum, Abdullah M Asiri, Md Imtaiyaz Hassan. Discovery of Hordenine as a Potential Inhibitor of Pyruvate Dehydrogenase Kinase 3: Implication in Lung Cancer Therapy. Biomedicines. 2020 May 14; 8(5):119.
26. Anas Shamsi, Saleha Anwar, Taj Mohammad, Mohamed F Alajmi, Afzal Hussain, Md Tabish Rehman, Gulam Mustafa Hasan, Asimul Islam, Md Imtaiyaz Hassan. MARK4 Inhibited by AChE Inhibitors, Donepezil and Rivastigmine Tartrate: Insights into Alzheimer's Disease Therapy. Biomolecules. 2020 May 20; 10(5):789.
27. Deeba Shamim Jairajpuri, Taj Mohammad, Kirtika Adhikari, Preeti Gupta, Gulam Mustafa Hasan, Mohamed F Alajmi, Md Tabish Rehman, Afzal Hussain, Md Imtaiyaz Hassan. Identification of Sphingosine Kinase-1 Inhibitors from Bioactive Natural Products Targeting Cancer Therapy. ACS Omega. 2020 Jun 8; 5(24):14720-14729.
28. Rashmi Dahiya, Taj Mohammad, Mohamed F Alajmi, Md Tabish Rehman, Gulam Mustafa Hasan, Afzal Hussain, Md Imtaiyaz Hassan. Insights into the Conserved Regulatory Mechanisms of Human and Yeast Aging. Biomolecules. 2020 Jun 9;10(6): E882.
29. Ahmad Abu Turab Naqvi, Kisa Fatima, Taj Mohammad, Urooj Fatima, Indrakant K Singh, Archana Singh, Shaikh Muhammad Atif, Gururao Hariprasad, Gulam Mustafa Hasan, Md Imtaiyaz Hassan. Insights into SARS-CoV-2 Genome, Structure, Evolution, Pathogenesis and Therapies: Structural Genomics Approach. Biochim Biophys Acta Mol Basis Dis. 2020 Jun 13; 1866(10):165878.
30. Saleha Anwar, Anas Shamsi, Mohd Shahbaaz, Aarfa Queen, Parvez Khan, Gulam Mustafa Hasan, Asimul Islam, Mohamed F Alajmi, Afzal Hussain, Faizan Ahmad, Md Imtaiyaz Hassan. Rosmarinic Acid Exhibits Anticancer Effects via MARK4 Inhibition. Scientific Reports. 2020 Jun 25; 10(1):10300.
31. Syed Ishraque Ahmad, Razi Ahmad, Mohd Shoeb Khan, Ravi Kant, Shumaila Shahid, Leela Gautam, Ghulam Mustafa Hasan, Md Imtaiyaz Hassan. Chitin and its derivatives: Structural properties and biomedical applications. Int J Biol Macromol. Volume 164, 1 December 2020, Pages 526-539
32. Sonam Roy, Taj Mohammad, Preeti Gupta, Rashmi Dahiya, Shahnaz Parveen, Suaib Luqman, Gulam Mustafa Hasan, Md Imtaiyaz Hassan. Discovery of Harmaline as a Potent Inhibitor of Sphingosine Kinase-1: A Chemopreventive Role in Lung Cancer. ACS Omega. 2020 Aug 20; 5(34):21550-21560.
33. Ilma Shakeel, Neha Basheer, Gulam Mustafa Hasan, Mohammad Afzal, Md Imtaiyaz Hassan. Polo-like Kinase 1 as an emerging drug target: structure, function and therapeutic implications. J Drug Target. 2020 Sep 14; 1-17.
34. Purva Asrani, Gulam Mustafa Hasan, Sukhwinder Singh Sohal, Md Imtaiyaz Hassan. Molecular Basis of Pathogenesis of Coronaviruses: A Comparative Genomics Approach to Planetary Health to Prevent Zoonotic Outbreaks in the 21st Century. OMICS. 2020 Sep 16.
35. Mohd Yousuf, Parvez Khan, Anas Shamsi, Mohd Shahbaaz, Gulam Mustafa Hasan, Qazi Mohd Rizwanul Haque, Alan Christoffels, Asimul Islam, and Md. Imtaiyaz Hassan. Inhibiting CDK6 Activity by Quercetin Is an Attractive Strategy for Cancer Therapy. ACS Omega October 14, 2020
36. Ayushi Rai, Saba Noor, Syed Ishraque Ahmad, Mohamed F Alajmi, Afzal Hussain 4, Hashim Abbas, Gulam Mustafa Hasan. Recent Advances and Implication of Bioengineered Nanomaterials in Cancer Theranostics. Medicina (Kaunas). 2021 Jan 21;57(2)
37. Indrakant Kumar Singh, Pratibha Kumari, Pooja Mittal, Amit Kumar, Bharti Singal, Gulam Mustafa Hasan, Rajiv Aggarwal, Mohammad Amjad Kamal, Archana Singh, Imtaiyaz Hassan. Emerging therapeutic approaches to COVID-19. Curr Pharm Des. 2021 Jan 25.
38. Deeba Shamim Jairajpuri, Afzal Hussain, Khalida Nasreen, Taj Mohammad, Farah Anjum, Md Tabish Rehman, Gulam Mustafa Hasan, Mohamed F Alajmi, Md Imtaiyaz Hassan. Identification of natural compounds as potent inhibitors of SARS-CoV-2 main protease using combined docking and molecular dynamics simulations. Saudi J Biol Sci. 2021 Apr; 28 (4):2423-2431
39. Fauzia Nazam, Sibhghatulla Shaikh, Nazia Nazam, Abdulaziz Saad Alshahrani, Gulam Mustafa Hasan, Md Imtaiyaz Hassan. Mechanistic insights into the pathogenesis of neurodegenerative diseases: towards the development of effective therapy. Mol Cell Biochem. 2021 Jul; 476(7):2739-2752
40. Azaj Ahmed, Anas Shamsi, Taj Mohammad, Gulam Mustafa Hasan, Asimul Islam, Md Imtaiyaz Hassan. Aurora B kinase: a potential drug target for cancer therapy. J Cancer Res Clin Oncol. 2021 Aug; 147(8):2187-2198.
41. Manzar Alam, Gulam Mustafa Hasan, Md Imtaiyaz Hassan. A review on the role of TANK-binding kinase 1 signaling in cancer. Int J Biol Macromol. 2021 Jul 31; 183:2364-2375.
42. Sabeeha Ali, Manzar Alam, Gulam Mustafa Hasan, Md Imtaiyaz Hassan. Potential therapeutic targets of Klebsiella pneumoniae: a multi-omics review perspective. Brief Funct Genomics. 2021 Aug 27
43. Aanchal Rathi, Dhiraj Kumar, Gulam Mustafa Hasan, Mohammad Mahfuzul Haque, Md Imtaiyaz Hassan. Therapeutic targeting of PIM KINASE signaling in cancer therapy: Structural and clinical prospects. Biochim Biophys Acta Gen Subj. 2021 Nov;1865(11):129995
44. Manzar Alam, Sabeeha Ali, Taj Mohammad, Gulam Mustafa Hasan, Dharmendra Kumar Yadav, Md Hassan. B Cell Lymphoma 2: A Potential Therapeutic Target for Cancer Therapy. Int. J. Mol. Sci. 2021, 22, 10442
45. Nashrah Sharif Khan, Parvez Khan, Mohammad Fawad Ansari, Saurabha Srivastava, Gulam Mustafa Hasan, Mohammad Husain, Md Imtaiyaz Hassan. Thienopyrimidine-Chalcone Hybrid Molecules Inhibit Fas-Activated Serine/Threonine Kinase: An Approach To Ameliorate Antiproliferation in Human Breast Cancer Cells. Mol Pharm. 2018 Sep 4;15(9):4173-4189
46. Mohd Yousuf, Anas Shamsi, Parvez Khan, Mohd Shahbaaz, Mohamed F AlAjmi, Afzal Hussain, Gulam Mustafa Hassan, Asimul Islam, Qazi Mohd Rizwanul Haque, Md Imtaiyaz Hassan. Ellagic Acid Controls Cell Proliferation and Induces Apoptosis in Breast Cancer Cells via Inhibition of Cyclin-Dependent Kinase 6. Int J Mol Sci. 2020 May 15;21(10):3526
47. Mustafa GH, Gorea RK, Rahman S, Khan MS. Diagnostic efficacy of cardiac troponin in post-mortem examination of acute myocardial infarction. Int J Eth Trauma Victimology 2015; 1(1):21-28.
48. Alaa Shafie, Shama Khan, Zehra, Taj Mohammad, Farah Anjum, Gulam Mustafa Hasan, Dharmendra Kumar Yadav, and Md. Imtaiyaz Hassan. Identification of Phytoconstituents as Potent Inhibitors of Casein Kinase-1 Alpha Using Virtual Screening and Molecular Dynamics Simulations. Pharmaceutics 2021, 13, 2157
49. Manzar Alam, Md Meraj Ansari, Saba Noor, Taj Mohammad, Gulam Mustafa Hasan, Syed Naqui Kazim, Md Imtaiyaz Hassan. Therapeutic targeting of TANK-binding kinase signaling towards anticancer drug development: Challenges and opportunities. Int J Biol Macromol. . 2022 May 15; 207:1022-1037
50. Manzar Alam, Gulam Mustafa Hasan, Md Meraj Ansari, Rishi Sharma, Dharmendra Kumar Yadav, Md Imtaiyaz Hassan. Therapeutic implications and clinical manifestations of thymoquinone. Phytochemistry. 2022 Aug; 200:113213
51. Mohd Yousuf, Manzar Alam, Anas Shamsi, Parvez Khan, Gulam Mustafa Hasan, Qazi M Rizwanul Haque, Md Imtaiyaz Hassan. Structure-guided design and development of cyclin-dependent kinase 4/6 inhibitors: A review on therapeutic implications. Int J Biol Macromol. 2022 Jul 22; 218:394-408.
52. Saleha Anwar, Moyad Shahwan, Gulam Mustafa Hasan, Asimul Islam, Md Imtaiyaz Hassan. Microtubule-affinity regulating kinase 4: A potential drug target for cancer therapy. Cell Signal. 2022 Aug 9; 99:110434.

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مواقع أعضاء هيئة التدريس

د.غلام مصطفى . حسن

المؤهلات العلمية

الاهتمامات البحثية

الخبرات

مهام ومسؤوليات

الأبحاث العلمية

تواصل مع قيادات الجامعة

إدارة العلاقات العامة والإعلام

Social

مواقع أعضاء هيئة التدريس

د.غلام مصطفى . حسن

المؤهلات العلمية

الاهتمامات البحثية

الخبرات

مهام ومسؤوليات

الأبحاث العلمية

إدارة العلاقات العامة والإعلام