أعضاء هيئة التدريس | مواقع أعضاء هيئة التدريس

د.أحمد عادل عاشور محمد

أستاذ مشارك قسم العقاقير كلية الصيدلة بالخرج

الخرج
ahmed.mohamed@psau.edu.sa

السيرة الذاتية
الأبحاث العلمية

المؤهلات العلمية

PhD: Faculty of Pharmacy, Mansoura University (Egypt)- Kyushu University (Japan) 2014 M.Sc.: Faculty of Pharmacy, Mansoura University 2010 B.Sc.: Faculty of Pharmacy, Mansoura University May 2007

الاهتمامات البحثية

Natural product chemistry; natural functional foods; bioactivity; Structure elucidation
Biotransformation of medicinal plant wastes into valuable chemicals and pharmaceuticals using two stage fermentation protocol.

الأبحاث العلمية

1- Amer, M., El-Sharkawy, S., Marzouk, A., Ashour, A.; “Chemical Constituents of Corncobs” Journal of Environmental Science, 40 (2), 251-258 (2011)
2- Amer, M., El-Sharkawy, S., Abdel Bar, F., Ashour, A.; “Phytochemical investigation of unused parts of Hibiscus Sabdariffa” Journal of American Science, 8 (12), 29-35 (2012).
3- Ashour, A., El-Sharkawy, S., Amer, M., Abdel Bar, F., Mera, A., Nagata, T., Kondo, R., Shimizu, K.; “Biotransformation of khellin to khellol by Aspergillus niger and the Evaluation of their Biological activities” The Open Bioactive Compounds Journal, 4, 1-3 (2013)
4- Ashour, A., El-Sharkawy, S., Amer, M., Abdel Bar, F., Kondo, R., Shimizu, K.; “Melanin Biosynthesis Inhibitory Activity of Compounds Isolated from unused parts of Ammi visinaga” Journal of Cosmetics, Dermatological Sciences and Application, 3 (3B), 40-43 (2013).
5- Ashour, A., Amer, M., Marzouk, A., Shimizu, K., Kondo, K., El-Sharkawy, S.; “Corncobs as a Potential Source of Functional Chemicals” Molecules , 18 (11), 13823-13830 (2013).
6- Ashour, A., El-Sharkawy, S., Amer, M., Abdel Bar, F., Katakura, Y., Miyamoto, T., Toyota, N., Hai Bang, T., Kondo, R., Shimizu, K.; “Rational design and synthesis of topoisomerase I and II inhibitors based on oleanolic acid moiety for new anti-cancer drugs” Bioorganic and Medicinal Chemistry, 22 (1), 211-220 (2014).
7- Ashour, A., El-Sharkawy, S., Amer, M., Marzouk, A., Awad, A., Kishikawa, A., Ohzono, M., Kondo, K., Shimizu, K.; “Production of citric acid from Corn cobs with its biological evulation” Journal of Cosmetics, Dermatological Sciences and Application, 4 (3), 141-149 (2014).
8- Tan, H., Ashour, A., Katakura, Y., Shimizu, K.; “A structure-activity relationship study on antiosteoclastogenesis effect of triterpenoids from the leaves of loquat (Eriobotrya japonica) ” Phytomedicine, 22, 498-503 (2015).
9- Kishikawa, A., Ashour, A., Zhu, Q., Yasuda, M., Ishikawa, H., Shimizu, K.; “Multiple biological effects of olive oil by-products such as leaves, stems, flowers, olive milled waste, fruit pulp, and seeds of the olive plant on skin” Phytotherpary Research, 29, 877-886 (2015).
10- Zaki, A., Ashour, A., Mira, A., Kishikawa, A., Nakagawa, T., Zhu, Q., Shimizu, K.; “ Biological activities of oleanolic acid derivatives from Calendula officinalis seeds” Phytotherpary Research, 30 (5), 835-841(2016).
11- Amen, Y., Zhu, Q., Hai Bang, T., Afifi, M., Halim, A., Ashour, A., Mira, A., Shimizu, K.; “ Lucidumol C, a new cytotoxic lanostanoid triterpene from Ganoderma lingzhi against human cancer cells” Journal of Natural Medicines, 70, 661-666 (2016).
12- Amen, Y., Zhu Q., Afifi, M., Halim, A., Ashour, A., Shimizu, K.; “New cytotoxic lanostanoid triterpenes from Ganoderma lingzhi ” Phytochemistry letter, 17, 64-70 (2016).
13- Elbermawi, A., Sallam, A., Ashour, A., Ebrahim, W., Lahloub, M., Saa, H.; “Biologically Active Metabolites from Penicillium sp., An Endophyte Isolated from Glaucium arabicum” Journal of American Science, 12, 33-41 (2016).
14- Sallam, A., Mira, A., Ashour, A., Shimizu, K.; “ Acetyl choline esterase inhibitors and melanin synthesis inhibitors from Salvia officinalis” Phytomedicine, 23 (10), 1005-1011 (2016).
15- Horiba, H., Nakagawa, T., Zhu, Q., Ashour, A., Watanabe, A., Shimizu, K.; “Biological Activities of Extracts from Different Parts of Cryptomeria japonica” Natural Product Communication, 11(9), 1337-1342 (2016).
16- Amen, Y., Zhu, Q., Tran, H., Afifi, M., Halim, A., Ashour, A., Shimizu, K.; “Partial contribution of Rho-kinase inhibition to the bioactivity of Ganoderma lingzhi and its isolated compounds: insights on discovery of natural Rho-kinase inhibitors” Journal of Natural Medicines, 71 (2), 380-388 (2017)
17- Amen, Y., Arung, E., Afifi, M., Halim, A., Ashour, A., Fujimoto, R., Goto, T., Shimizu, K.; “Melanogenesis inhibitors from Coix lacryma-jobi seeds in B16-F10 melanoma cells” Natural Product Research, 31 (23), 2712-2718 (2017).
18- Lahloub, M.F., Amer, M., Zaki, A., Ashour, A., Amen, Y., Samara, R.; “Bioactive compounds from Malva rotundifolia L.” World Journal of Pharmaceutical Science, 5(8), 171-176 (2017).
19- Amen, Y., Arung, E., Afifi, M., Halim, A., Ashour, A., Shimizu, K.; “Rho-kinase inhibitors from Adlay seeds” Natural Product Research, 32 (16), 1955-1959 (2018).
20- Satria, D., Amen, Y., Niwa, Y., Ashour, A., Allam, A., Shimizu, K., “Lucidumol D, a new lanostane-type triterpene from fruiting bodies of Reishi (Ganoderma lingzhi)” Natural Product Research, 33 (2), 189-195 (2018).
21- Taga, Y., Hayashida, O., Ashour, A., Amen, Y., Kusubata, M., Ogawa-Goto, K., Shimizu, k., Hattori, S.; “Characterization of Angiotensin-Converting Enzyme Inhibitory Activity of X-Hyp-Gly-Type Tripeptides: Importance of Collagen-Specific Prolyl Hydroxylation” Journal of Agricultural and Food Chemistry, 66 (33), 8737-8743 (2018).
22- Ashour, A., Amen, Y., Nakagawa, T., Niwa, Y., Mira, A., Ohnuki, K., Murakami, S., Imao, M., Shimizu, K.; “A New aliphatic ester of hydroxy salicyclic acid from fermented Carica papaya L. preparation with a potential hair growth stimulating activity” Natural Product Research, Accepted (2018).
23- Nakagawa, T., Ashour, A., Amen, Y., Ohnuki, K., Fujimoto, N., Shimizu, K.; “Antioxidant and anti-lipase compounds isolated from heartwood of Yakushima native cedar (Cryptomeria japonica)” Journal of Wood Chemistry and Technology, Accepted (2019).
24- Ashour, A., Amen, Y., Allam, A., Kudo, T., Nagata, M., Ohnuki, K., Shimizu, K.; “New isoindolinones from the fruiting bodies of the fungus Hericium erinaceus” Phytochemistry letters, 32, 10-14 (2019).
25- Elbermawi, A., Halim, A., Mansour, E., Ahmad, K., Ashour, A., Amen, Y., Shimizu, K.; “A new glucoside with a potent α-glucosidase inhibitory activity from Lycium schweinfurthii” Natural Product Research, Accepted (2019).
26- Mwakalukwa, R., Ashour, A., Amen, Y., Niwa, Y., Tamrakar, S., Miyamoto, T., Shimizu, K.; “Anti-allergic activity of polyphenolic compounds isolated from olive mill wastes” Journal of Functional Foods, 58, 207-217 (2019).
27- Nakagawa, T., Ashour, A., Amen, Y., Koba, Y., Ohnuki, K., and Shimizu, K.; “α-Glucosidase inhibitory activity of resin from Sakhalin fir tree (Abies sachalinensis) and its bioactive compounds” Natural Product Communication, 1-4 (2019).
28- Abdelkarem, F., Desoky, E., Nafady, A., Allam, A., Mahdy, A., Ashour, A., Mohamed, G., Miyamoto, T., Shimizu, K.; “Two new polyhydroxylated steroids from Egyptian soft coral Heteroxenia fuscescens (Fam.; Xeniidae)” Natural Product Research, 35 (2), 236-243 (2021).
29- Elkattan, A., Gohar, A., Amer, M., Naeem, Z., Ashour, A., Shimizu, K.; “Melanin Synthesis inhibitors from Olea europeae” Records of Natural Products, Accepted (2019)
30- Zaki, A., Ashour, A., Qiu, L.; “New sesquiterpene glycoside ester with antiprotozoal activity from the flowers of Calendula officinalis L” Natural Product Research, Accepted (2020).
31- Hassan, A., Ashour, A., Amen, Y., Nagata, M., El-Toumy, S., Shimizu, K.; “A new cycloartane triterpene and other phytoconstituents from the aerial parts of Euphorbia dendroides” Natural Product Research, Accepted (2020).
32- Shams, A., Soliman, A., Ashour, A., Marzouk, A, El-Sharkawy, S.; “Utilization of Wood Industrial Wastes for Production of Chemicals and Pharmaceuticals” Indian Journal of Science and Technology, Accepted (2020).
33- Zaki, A., Al‐Karmalawy, A., El-Amier, Y., Ashour, A.; “Molecular docking reveals the potential of Cleome amblyocarpa isolated compounds to inhibit COVID-19 virus main protease” New Journal of Chemistry, 44, 16752-16758 (2020).
34- Abdelkarem, F., Desoky, E., Nafady, A., Allam, A., Mahdy, A., Ashour, A., Shimizu, K.; “Diadema setosum: Isolation of bioactive secondary metabolites with cytotoxic activity toward human cervical cancer” Natural Product Research, Accepted (2020).
35- Samra, R., Soliman, A., Zaki, A., Ashour, A., Al‐Karmalawy, A., Hassan, M., Zaghloul, A.; “Bioassay-guided isolation of a new cytotoxic Ceramide from Cyperus rotundus L.” South African Journal of Botany, Accepted (2021).
36- Elbermawi, A., Halim, A., Mansour, E., Ahmad, K., Elsbaey, M., Ashour, A., Amen, Y., El-Gamil, M., Miyamoto, T., Shimizu, K.; “Lycium schweinfurthii: new secondary metabolites and their cytotoxic activities” Natural Product Research, Accepted (2021).
37- Zaki, A., Ashour, A., Elhady, S., Darwish, K., Al‐Karmalawy, A.; “Calendulaglycoside A Showing Potential Activity Against SARS-CoV-2 Main Protease: Molecular Docking, Molecular Dynamics, and SAR Studies” journal of traditional and complementary medicine, Accepted (2021).
38- Allam, A., Amen, Y., Ashour, A., Assaf, H., Hassan, H., Mohamed, I., Sayed, A., Shimizu, K.; “In silico study of natural compounds from Sesame against COVID-19 by targeting Mpro, PLpro and RdRp” RSC advances, Accepted (2021).
39- Zaki, A., Al‐Karmalawy, A., Khodir, A., El-Amier, Y., Ashour, A.; “Isolation of cytotoxic active compounds from Reichardia tingitana with investigation of apoptosis mechanistic induction: in silico, in vitro, and SAR studies” South African Journal of Botany, 144, 115-123 (2022).
40- Zaki, A., Kaddah, M., Abulkhair, H., Ashour, A.; “Unravelling the antifungal and antiprotozoal activities and LC-MS/MS quantification of steroidal saponins isolated from Panicum turgidum” RSC advances, Accepted (2022).
41- Zaki, A., El-Amier, Y., Ashour, A.; “Two new cytotoxic tetralin derivatives from Panicum turgidum” Natural Product Research, Accepted (2022).
42- Saleh, M., Antar, S., Abdo, W., Ashour, A., Zaki, A.; “Genistin Modulates High-Mobility Group Box Protein 1 (HMGB1) and Nuclear Factor kappa-B (NF-κB) in Ehrlich-Ascites-Carcinoma-Bearing Mice” Environmental Science and Pollution Research, Accepted (2022).
43- Elbermawi, A., Ali, A., Amen, Y., Ashour, A., Ahmad, K., Mansour, E., Halim, A.; “Anti-diabetic activities of phenolic compounds of Alternaria sp. an endophyte isolated from the leaves of desert plants growing in Egypt” RSC advances, Accepted (2022).

للاتصال من داخل الجامعة 1200
للاتصال من خارج الجامعة 011-588-1200
البريد الإلكترونى pr@psau.edu.sa
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مواقع أعضاء هيئة التدريس

د.أحمد عادل عاشور محمد

المؤهلات العلمية

الاهتمامات البحثية

الأبحاث العلمية

تواصل مع قيادات الجامعة

إدارة العلاقات العامة والإعلام

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مواقع أعضاء هيئة التدريس

د.أحمد عادل عاشور محمد

المؤهلات العلمية

الاهتمامات البحثية

الأبحاث العلمية

إدارة العلاقات العامة والإعلام